F5Y1B6 · F5Y1B6_RAMTT

Function

function

Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

Catalytic activity

Features

Showing features for active site.

118720406080100120140160180
TypeIDPosition(s)Description
Active site47Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionNADH-dependent peroxiredoxin activity
Molecular Functionthioredoxin peroxidase activity
Biological Processcell redox homeostasis
Biological Processcellular response to stress
Biological Processhydrogen peroxide catabolic process
Biological Processresponse to oxidative stress

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Alkyl hydroperoxide reductase C
  • EC number
  • Alternative names
    • Peroxiredoxin
    • Thioredoxin peroxidase

Gene names

    • Name
      ahpC
    • Ordered locus names
      Rta_24190

Organism names

Accessions

  • Primary accession
    F5Y1B6

Proteomes

Subcellular Location

Keywords

PTM/Processing

Keywords

Interaction

Subunit

Homodimer; disulfide-linked, upon oxidation. 5 homodimers assemble to form a ring-like decamer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-157Thioredoxin

Sequence similarities

Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    187
  • Mass (Da)
    20,445
  • Last updated
    2011-07-27 v1
  • Checksum
    416A94A5D0D6916C
MSLINTQVVPFKTTAFHNGKFVPVSDESLKGKWSVLIFMPAAFTFNCPTEVEDAAENYAEFQKLGAEVYIVTTDTHFSHKVWHETSAAVGKAKFPLVGDPTHTLTNAFGVHIPEEGLALRGTFIVNPEGVVKTAEIHSNEIARDVKETLRKLKAAQYTAAHPGEVCPAKWNEGAKTLKPSLDLVGKI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000245
EMBL· GenBank· DDBJ
AEG93517.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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