F5B8V9 · CONB1_LUPAN
- ProteinConglutin beta 1
- GeneBETA1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids611 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Seed storage protein. Accumulates during seed development and is hydrolyzed after germination to provide a carbon and nitrogen source for the developing seedling.
Miscellaneous
The variability of the residues taking part of IgE-binding epitopes might be responsible of the difference in cross-reactivity among legumes.
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Molecular Function | nutrient reservoir activity |
Keywords
- Molecular function
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameConglutin beta 1
- Allergen nameLup an 1
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Fabales > Fabaceae > Papilionoideae > 50 kb inversion clade > genistoids sensu lato > core genistoids > Genisteae > Lupinus
Accessions
- Primary accessionF5B8V9
Genome annotation databases
Phenotypes & Variants
Allergenic properties
Causes an allergic reaction in human. Lup an 1 is the major lupin allergen.
Keywords
- Disease
Protein family/group databases
PTM/Processing
Features
Showing features for signal, chain, glycosylation.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-30 | |||||
Sequence: MAKMRVRLPMLILLLGVVFLLAASIGIAYG | ||||||
Chain | PRO_5003326254 | 31-611 | Conglutin beta 1 | |||
Sequence: EKDFTKNPPKEREEEEHEPRQQPRPRQQEEQEREHRREEKHDGEPSRGRSQSEESQEEEHERRREHHREREQEQQPRPQRRQEEEEEEEEWQPRRQRPQSRREEREEREQEQGSSSGSQRGSGDERRQHRERRVHREEREQEQDSRSDSRRQRNPYHFSSNRFQTYYRNRNGQIRVLERFNQRTNRLENLQNYRIIEFQSKPNTLILPKHSDADFILVVLNGRATITIVNPDKRQVYNLEQGDALRLPAGTTSYILNPDDNQNLRVAKLAIPINNPGKLYDFYPSTTKDQQSYFSGFSKNTLEATFNTRYEEIERVLLGDDELQENEKQRRGQEQSHQDEGVIVRVSKKQIQELRKHAQSSSGEGKPSESGPFNLRSNKPIYSNKFGNFYEITPDINPQFQDLNISLTFTEINEGALLLPHYNSKAIFIVVVDEGEGNYELVGIRDQQRQQDEQEEEYEQGEEEVRRYSDKLSKGDVFIIPAGHPLSINASSNLRLLGFGINANENQRNFLAGSEDNVIKQLDREVKELTFPGSIEDVERLIKNQQQSYFANAQPQQQQQREKEGRRGRRGPISSILNALY | ||||||
Glycosylation | 434 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 519 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N |
Keywords
- PTM
PTM databases
Expression
Developmental stage
Increased expression during seed filling, with a maximum between 33 and 38 days after anthesis.
Interaction
Subunit
Component of globulins complexes which accumulate in seeds.
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 32-194 | Disordered | ||||
Sequence: KDFTKNPPKEREEEEHEPRQQPRPRQQEEQEREHRREEKHDGEPSRGRSQSEESQEEEHERRREHHREREQEQQPRPQRRQEEEEEEEEWQPRRQRPQSRREEREEREQEQGSSSGSQRGSGDERRQHRERRVHREEREQEQDSRSDSRRQRNPYHFSSNRFQ | ||||||
Compositional bias | 34-143 | Basic and acidic residues | ||||
Sequence: FTKNPPKEREEEEHEPRQQPRPRQQEEQEREHRREEKHDGEPSRGRSQSEESQEEEHERRREHHREREQEQQPRPQRRQEEEEEEEEWQPRRQRPQSRREEREEREQEQG | ||||||
Compositional bias | 152-185 | Basic and acidic residues | ||||
Sequence: SGDERRQHRERRVHREEREQEQDSRSDSRRQRNP | ||||||
Domain | 186-344 | Cupin type-1 1 | ||||
Sequence: YHFSSNRFQTYYRNRNGQIRVLERFNQRTNRLENLQNYRIIEFQSKPNTLILPKHSDADFILVVLNGRATITIVNPDKRQVYNLEQGDALRLPAGTTSYILNPDDNQNLRVAKLAIPINNPGKLYDFYPSTTKDQQSYFSGFSKNTLEATFNTRYEEIE | ||||||
Region | 384-407 | Disordered | ||||
Sequence: LRKHAQSSSGEGKPSESGPFNLRS | ||||||
Compositional bias | 393-407 | Polar residues | ||||
Sequence: GEGKPSESGPFNLRS | ||||||
Domain | 403-569 | Cupin type-1 2 | ||||
Sequence: FNLRSNKPIYSNKFGNFYEITPDINPQFQDLNISLTFTEINEGALLLPHYNSKAIFIVVVDEGEGNYELVGIRDQQRQQDEQEEEYEQGEEEVRRYSDKLSKGDVFIIPAGHPLSINASSNLRLLGFGINANENQRNFLAGSEDNVIKQLDREVKELTFPGSIEDVE | ||||||
Region | 476-495 | Disordered | ||||
Sequence: DQQRQQDEQEEEYEQGEEEV | ||||||
Region | 580-600 | Disordered | ||||
Sequence: FANAQPQQQQQREKEGRRGRR |
Sequence similarities
Belongs to the 7S seed storage protein family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length611
- Mass (Da)71,926
- Last updated2011-06-28 v1
- Checksum9B6147810F865A1E
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 34-143 | Basic and acidic residues | ||||
Sequence: FTKNPPKEREEEEHEPRQQPRPRQQEEQEREHRREEKHDGEPSRGRSQSEESQEEEHERRREHHREREQEQQPRPQRRQEEEEEEEEWQPRRQRPQSRREEREEREQEQG | ||||||
Compositional bias | 152-185 | Basic and acidic residues | ||||
Sequence: SGDERRQHRERRVHREEREQEQDSRSDSRRQRNP | ||||||
Compositional bias | 393-407 | Polar residues | ||||
Sequence: GEGKPSESGPFNLRS |
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
HQ670409 EMBL· GenBank· DDBJ | AEB33712.1 EMBL· GenBank· DDBJ | mRNA |