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F5B5U3 · F5B5U3_9GOBI

Function

function

Photoreceptor required for image-forming vision at low light intensity. While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Features

Showing features for site, binding site.

126020406080100120140160180200220240260
Type
IDPosition(s)Description
Site84Plays an important role in the conformation switch to the active conformation
Binding site172Zn2+ (UniProtKB | ChEBI)
Binding site250Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmembrane
Cellular Componentphotoreceptor outer segment
Molecular FunctionG protein-coupled photoreceptor activity
Molecular Functionmetal ion binding
Biological Processcellular response to light stimulus
Biological Processphototransduction
Biological Processvisual perception

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Rhodopsin

Gene names

    • Name
      Rhod

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 40A18
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Gobiaria > Gobiiformes > Gobioidei > Gobiidae > Sicydiinae > Sicyopus

Accessions

  • Primary accession
    F5B5U3

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-34Helical
Transmembrane46-66Helical
Transmembrane86-104Helical
Transmembrane124-144Helical
Transmembrane174-194Helical
Transmembrane225-247Helical

Keywords

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond81↔158

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain25-260G-protein coupled receptors family 1 profile

Sequence similarities

Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.

Keywords

Family and domain databases

Protein family/group databases

Sequence

  • Sequence status
    Fragment
  • Length
    260
  • Mass (Da)
    29,278
  • Last updated
    2011-06-28 v1
  • MD5 Checksum
    2D7FA389ECCEA5168C7D9DC8107C0211
YLVNPAAYAALGAYMFFLILAGFPINFLTLYVTIEHKKLRTPLNYILLNLAVADLFMVFGGFTTTMYTSMHGYFVLGRLGCNLEGFFATLGGEIGLWSLVVLAIERWIVVCKPISNFRFGENHAIMGVALTWIMACSCAVPPLVGWSRYIPEGMQCSCGVDYYTRAEGFNNESFVIYMFIVHFSIPFTVIFFCYGRLLCAVKEAAAAQQESETTQRAEREVTRMVVIMVIAFLVSWLPYASVAWYIFTHQGSEFGPLFMT

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue260

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HQ639197
EMBL· GenBank· DDBJ
AEC05109.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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