F4JY12 · GFS12_ARATH

Function

function

May act predominantly to suppress BCHC1, which itself is a negative factor in protein storage vacuole (PSV) trafficking regulation and plant effector triggered immunity (ETI). Required for ETI, but not for cell death.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentCul4-RING E3 ubiquitin ligase complex
Molecular FunctionATP binding
Molecular Functionprotein kinase activity
Biological Processdefense response to bacterium
Biological Processprotein phosphorylation
Biological Processprotein targeting to vacuole

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein GFS12
  • EC number
  • Alternative names
    • BEACH domain-containing protein D
    • BEACH-domain homolog D
    • GREEN FLUORESCENT SEED 12

Gene names

    • Name
      GFS12
    • Synonyms
      BCHD
    • ORF names
      T28N17.10
    • Ordered locus names
      At5g18525

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    F4JY12
  • Secondary accessions
    • B5B8Z0
    • Q8VZH9

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Phenotypes & Variants

Disruption phenotype

No visible phenotype. Accumulation of unprocessed 12S globulin in the seeds.

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 123 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004340311-1639Protein GFS12

Proteomic databases

PTM databases

Expression

Tissue specificity

Weakly expressed in the cotyledons of germinating seedlings. Restricted to the vascular tissues of cotyledons. Detected in root tips, apical meristem, young flower buds and receptacles.

Gene expression databases

Interaction

Subunit

Interacts (via protein kinase 2 domain) with BCHC1 (via PH-BEACH domain).

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, repeat, region.

Type
IDPosition(s)Description
Domain206-294Protein kinase 1
Domain336-608BEACH
Domain715-788Protein kinase 2
Repeat1290-1333WD 1
Repeat1336-1373WD 2
Region1377-1399Disordered
Repeat1465-1499WD 3
Repeat1511-1549WD 4
Repeat1609-1639WD 5

Sequence similarities

Belongs to the protein kinase superfamily. Tyr protein kinase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,639
  • Mass (Da)
    183,399
  • Last updated
    2011-06-28 v1
  • Checksum
    2B71A76D1D035792
MRGEDSDLCFDCLDQRINSDFSDQIVFSYGVSDSPLPFGSSAVVKVSDSSEEFSASCSSCESTSSQFILEYLRKDEHGCLAKYVDKFVVKDREGNSNDAVESDECLDCSTSGSQATEDDDTENITCGSVTCEHSGSFSCWRTVAALLPIAQIRKCSASELQKLASSFHYECPEDQILASLHRLIDGKSSGQATHSFLCLLLGLPLLEEKSKLRCLRHPNLSPVLGLLTSSDCLVSVLPKAPYTLENILYYSPSAIKSEWHRNFIIYQLLSALAHLHGLKVSHGDIRPSNILLSDSLWSWLTIYSKPDLGSVDANSSASRRRWCVEGCYSYGLYADLKISSHLDWQTHFDKWWKGELSNFEYLLVLNKLAGRRWGDHTFHPVMPWVIDFSKKPENDSDSGWRDLRKSKWRLAKGDEQLDFTYSTFEFPHHVSDECLSELAVCSYKARRLPLSVLRKAVRSVYEPNEYPSDMQRLYDWTPDECIPEFYCDPRIFCSLHPSMSDLAVPPWASSPDEFIRLHRDALESPHVSSLIHHWIDITFGYKMSGHAAITAKNVMLSSSEPTVPRSVGRRQLFFRPHPVRLGFSREKEQSRNELEMHTFHGFGVDNKRSVILLADEYLEETEEASAFSDHATHLCPKYHLRENLVESPLHVSYSENTKKVNTSLPGTSKNKGLSSRISLNYLLEHMEVRDEASTELQELLQWRQDFCTGNISKDIAGDIFSIGCVLAELYLMKPLFNSVSLATYLEGGDLPELIKELPPPTQVIVEACIEQDWRRRPSAKSLLDSPYFSATVRSAHLFAAPLQLLAKGQTRLCYAASFAKQGVLKVMGTFVAEMCAVYCLPLVTTPLSEDECELAYVLLKEFTKSLTPMAVQRLVLPSIQKILLTTGYSHLKVSLLQDSFVRELWNQIGKRVYLEMIHPLVISNLYNSPDKISASAASVLLIGSSEELGAPVTVHQTILPLISYFGKGICTDGIDVLVRIGRLLGVNFIVKQMLPLLEHVVCFCIDLSSMKKPEPVHSWCSLALSDCLITLDGLVALISDELLIHELTKGRLCLHVRVLMQKNLELRVLQFAATSLMSICQRIGQEMTALHVLPQLKELFDEFAFSEKSTDASDSLSWKIRTAEQKFHPESPIKSRMDLVLLLYPSFASLLGMEKLRQGCPTWLLLEQYLLKHHNWKWEYTGRSSRYNMEARPVLKQGPASKHTPKVLLNGSGRSVPQSQGLRNSNHLKLHIHVPVEGQEAVLNPLVHEPWSWFPSPVTCWDGLDIGRFGNPKDENRWKIRASVLSSARAHHGALRSLVVSEDECTVFTSGIDPGFKGSVQKWELASLSCVSSYHAHEEVVNDIGILSSTGKVASCDGTIHVWNSQTGKLISLFSESPSDQDQASSDPSSKNNSNPCNRHASHGLSSGIFDENLYTCMHYLEYMDQLIVGTGFGALRFIDLARGQKLELWGGEAIESGFTSLVSALCSGGSQTKHGDGASVSPSWIAAGFSSGQCRLFDLRENGFISSWRAHDGYVTKLVAPESHLLVSSSLDKTLRIWDLRKSWTPQPFVVKGHNDGVSGFSIWGKDVISISRNNIGIFSLAKSQDEEEQQQQRIIPQKLYMAEKGGRVKSDLSTICVLPFSRLFIVGAHDGHLRICC

Sequence caution

The sequence AAL36064.1 differs from that shown. Reason: Erroneous initiation Truncated N-terminus.

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict978-984in Ref. 3; CAQ77322

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC069328
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
CP002688
EMBL· GenBank· DDBJ
AED92575.1
EMBL· GenBank· DDBJ
Genomic DNA
FM180203
EMBL· GenBank· DDBJ
CAQ77322.1
EMBL· GenBank· DDBJ
mRNA
AY064158
EMBL· GenBank· DDBJ
AAL36064.1
EMBL· GenBank· DDBJ
mRNA Different initiation
AY143925
EMBL· GenBank· DDBJ
AAN28864.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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