F4JPA9 · F4JPA9_ARATH
- Protein4-hydroxybenzoate polyprenyltransferase, mitochondrial
- GenePPT1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids429 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
Catalytic activity
- 4-hydroxybenzoate + an all-trans-polyprenyl diphosphate = a 4-hydroxy-3-all-trans-polyprenylbenzoate + diphosphate
CHEBI:17879 + an all-trans-polyprenyl diphosphate RHEA-COMP:9564 = a 4-hydroxy-3-all-trans-polyprenylbenzoate RHEA-COMP:9514 + CHEBI:33019
Cofactor
Pathway
Cofactor biosynthesis; ubiquinone biosynthesis.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Molecular Function | 4-hydroxybenzoate decaprenyltransferase activity | |
Molecular Function | 4-hydroxybenzoate nonaprenyltransferase activity | |
Molecular Function | 4-hydroxybenzoate octaprenyltransferase activity | |
Biological Process | embryo development ending in seed dormancy | |
Biological Process | isoprenoid biosynthetic process | |
Biological Process | ubiquinone biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name4-hydroxybenzoate polyprenyltransferase, mitochondrial
- EC number
- Short names4-HB polyprenyltransferase
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionF4JPA9
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 137-154 | Helical | ||||
Sequence: IGTWLLAWPCMWSIALAA | ||||||
Transmembrane | 166-186 | Helical | ||||
Sequence: ALFGCGALLLRGAGCTINDLL | ||||||
Transmembrane | 206-227 | Helical | ||||
Sequence: LLTPFQGIGFLGLQLLLGLGIL | ||||||
Transmembrane | 256-275 | Helical | ||||
Sequence: FWPQAFLGLTINWGALLGWT | ||||||
Transmembrane | 281-303 | Helical | ||||
Sequence: IAPSIVLPLYLSGVCWTLVYDTI |
Keywords
- Cellular component
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Structure
Sequence
- Sequence statusComplete
- Length429
- Mass (Da)47,364
- Last updated2011-06-28 v1
- Checksum266009845BF3F1B9
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q93YP7 | COQ2_ARATH | PPT1 | 407 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP002687 EMBL· GenBank· DDBJ | AEE84792.1 EMBL· GenBank· DDBJ | Genomic DNA |