F4JBY2 · F4JBY2_ARATH
- Proteintransketolase
- GeneTKL1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids740 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
Catalytic activity
- D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate
Cofactor
Protein has several cofactor binding sites:
Note: Binds 1 thiamine pyrophosphate per subunit. During the reaction, the substrate forms a covalent intermediate with the cofactor.
Features
Showing features for binding site, site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 103 | substrate | |||
Site | 103 | Important for catalytic activity | |||
Binding site | 143 | thiamine diphosphate (UniProtKB | ChEBI) | |||
Binding site | 191-193 | thiamine diphosphate (UniProtKB | ChEBI) | |||
Binding site | 233 | thiamine diphosphate (UniProtKB | ChEBI) | |||
Binding site | 262 | thiamine diphosphate (UniProtKB | ChEBI) | |||
Binding site | 339 | substrate | |||
Binding site | 339 | thiamine diphosphate (UniProtKB | ChEBI) | |||
Site | 339 | Important for catalytic activity | |||
Binding site | 433 | substrate | |||
Binding site | 460 | substrate | |||
Active site | 487 | Proton donor | |||
Binding site | 514 | thiamine diphosphate (UniProtKB | ChEBI) | |||
Binding site | 538 | substrate | |||
Binding site | 546 | substrate | |||
Binding site | 550 | substrate | |||
Binding site | 597 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | metal ion binding | |
Molecular Function | transketolase activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametransketolase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionF4JBY2
Proteomes
Organism-specific databases
Genome annotation databases
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 22-52 | Disordered | |||
Domain | 430-602 | Transketolase-like pyrimidine-binding | |||
Sequence similarities
Belongs to the transketolase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length740
- Mass (Da)79,839
- Last updated2011-06-28 v1
- MD5 ChecksumDEDF18BDBD8D105CCCF9979561429C03
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q8RWV0 | TKTC1_ARATH | TKL-1 | 741 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP002686 EMBL· GenBank· DDBJ | AEE80104.1 EMBL· GenBank· DDBJ | Genomic DNA |