F4J4C8 · EVN_ARATH

Function

function

Essential for pollen development. Involved in protein N-glycosylation in the endoplasmic reticulum (ER), especially in the female gametophyte. Mediates pollen tube (PT) reception in synergids through protein glycosylation.

Catalytic activity

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentendoplasmic reticulum
Cellular Componentendoplasmic reticulum membrane
Molecular Functiondolichol kinase activity
Biological Processpollen development
Biological Processpollen tube reception
Biological Processprotein glycosylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Dolichol kinase EVAN
  • EC number

Gene names

    • Name
      EVN
    • ORF names
      F14D17.110
    • Ordered locus names
      At3g45040

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    F4J4C8
  • Secondary accessions
    • Q8VXX8
    • Q9LXH2

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Features

Showing features for topological domain, transmembrane.

Type
IDPosition(s)Description
Topological domain1-22Cytoplasmic
Transmembrane23-43Helical
Topological domain44-67Lumenal
Transmembrane68-88Helical
Topological domain89-108Cytoplasmic
Transmembrane109-129Helical
Topological domain130-147Lumenal
Transmembrane148-168Helical
Topological domain169-178Cytoplasmic
Transmembrane179-199Helical
Topological domain200-207Lumenal
Transmembrane208-228Helical
Topological domain229-252Cytoplasmic
Transmembrane253-273Helical
Topological domain274-296Lumenal
Transmembrane297-317Helical
Topological domain318-340Cytoplasmic
Transmembrane341-361Helical
Topological domain362-369Lumenal
Transmembrane370-390Helical
Topological domain391-393Cytoplasmic
Transmembrane394-414Helical
Topological domain415-440Lumenal
Transmembrane441-461Helical
Topological domain462-464Cytoplasmic
Transmembrane465-485Helical
Topological domain486-508Lumenal
Transmembrane509-529Helical
Topological domain530-548Cytoplasmic
Transmembrane549-569Helical

Keywords

Phenotypes & Variants

Disruption phenotype

Pollen tube (PT) overgrowth inside the female gametophyte (FG) without PT rupture. Degenerated pollen grains before maturation, during the early tricellular stage.

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 60 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain, glycosylation.

Type
IDPosition(s)Description
ChainPRO_00004336351-569Dolichol kinase EVAN
Glycosylation289N-linked (GlcNAc...) asparagine

Keywords

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region487-503CTP-binding

Sequence similarities

Belongs to the polyprenol kinase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    569
  • Mass (Da)
    63,136
  • Last updated
    2011-06-28 v1
  • MD5 Checksum
    3821F6C31993DE5F1D0B04BC9E774F67
MKTTATSFVTGERVVVFVVVSRILLSLPLSLISHGFSLFLLSLSAFLVEIRVETSPFLLSHFSSRRGASSGILLGAVTLPSVMISKLVQLSRAISIHEAEQDELAHVTMQYWAASASCCAILIYLSVIMSQVRKDESLSSSSIWLTRVSLTGTVLYGVACFVSLSMISHTGLNTSLKMLWMLFHGLAAVKLIRHLLCTFPSCASIGEALLVTSGLVLYFGDFLACTIAKIFEKLIPVDLVSISYGIKRTETGIIVQGLLLGLLLFPMVFRFVLHIYESSLRKRDARQRNCSDAAKSVLFFVSLLFFMVVAVPSWMQFVHDFNQHPFLWVLTFVFSEPLKRLSLCIYWILLIVVSVSRFYNISRSSKVERILLRKYYHLMAVLMFLPALVLQPKFLDLAFGAALAVFVALEIIRIWRIQPLGEPLHQFMNAFTDHRDSEHLIVSHFSLLLGCALPIWMSSGFNDRALSPFAGILSLGIGDTMASMVGHKYGVLRWSKTGKKTVEGTAAGITSMMAVCFVLVPILASMGYILSQGWWSLLVAVTATGMLEAYTAQLDNAFIPLVFYSLLCL

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A1I9LMJ1A0A1I9LMJ1_ARATHDOK1521
A0A1I9LMJ2A0A1I9LMJ2_ARATHDOK1552

Sequence caution

The sequence CAB89319.1 differs from that shown. Reason: Erroneous gene model prediction

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict411in Ref. 3; AAL67067
Sequence conflict419in Ref. 3; AAL67067

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AL353992
EMBL· GenBank· DDBJ
CAB89319.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
CP002686
EMBL· GenBank· DDBJ
AEE77982.1
EMBL· GenBank· DDBJ
Genomic DNA
AY074371
EMBL· GenBank· DDBJ
AAL67067.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help