F4I529 · F4I529_ARATH
- ProteinCalreticulin
- GeneCRT1A
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids424 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 112 | an alpha-D-glucoside (UniProtKB | ChEBI) | |||
Binding site | 114 | an alpha-D-glucoside (UniProtKB | ChEBI) | |||
Binding site | 131 | an alpha-D-glucoside (UniProtKB | ChEBI) | |||
Binding site | 138 | an alpha-D-glucoside (UniProtKB | ChEBI) | |||
Binding site | 321 | an alpha-D-glucoside (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum lumen | |
Molecular Function | calcium ion binding | |
Molecular Function | unfolded protein binding | |
Biological Process | protein folding |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Recommended nameCalreticulin
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionF4I529
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-22 | ||||
Chain | PRO_5003309565 | 23-424 | Calreticulin | ||
Disulfide bond | 108↔140 | ||||
Keywords
- PTM
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for compositional bias, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 213-253 | Basic and acidic residues | |||
Region | 213-279 | Disordered | |||
Compositional bias | 353-378 | Basic and acidic residues | |||
Region | 353-424 | Disordered | |||
Sequence similarities
Belongs to the calreticulin family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length424
- Mass (Da)49,143
- Last updated2011-06-28 v1
- ChecksumF73ABE97B6015235
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
O04151 | CALR1_ARATH | CRT1 | 425 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 213-253 | Basic and acidic residues | |||
Compositional bias | 353-378 | Basic and acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP002684 EMBL· GenBank· DDBJ | AEE33380.1 EMBL· GenBank· DDBJ | Genomic DNA |