F4FZT3 · F4FZT3_METCR
- Protein2-oxoacid oxidoreductase (ferredoxin)
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids273 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
function
Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as 2-oxoglutarate, pyruvate and 2-oxobutyrate to form their CoA derivatives.
Catalytic activity
- a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = an acyl-CoA + CO2 + H+ + 2 reduced [2Fe-2S]-[ferredoxin]
Cofactor
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Molecular Function | 2-oxobutyrate synthase activity | |
Molecular Function | 2-oxoglutarate synthase activity | |
Molecular Function | pyruvate synthase activity |
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name2-oxoacid oxidoreductase (ferredoxin)
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageArchaea > Thermoproteota > Thermoprotei > Sulfolobales > Sulfolobaceae > Metallosphaera
Accessions
- Primary accessionF4FZT3
Proteomes
Interaction
Subunit
Heterodimer composed of an alpha and a beta subunit.
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 38-256 | Transketolase N-terminal | ||||
Sequence: QSIHVGSSLSSVEILTALEFKVLRDSSDPINRDWLILSKGHAAPALYAVLHEKGLIKEEELWKIQDISGLLQGHPETFIPGVDMSTGSLGQGLSFGIGVATGIKMSKGAGRVFVIMGDGEQDEGEIWEAMTHAIARNLDNLVAIIEMNGFQLDEATKDVKPKEFLPEVWRAVGWRVFNCDGHDIASVISTIDEALKSKRPAVIFAETRRGKGFTPIENT |
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length273
- Mass (Da)30,096
- Last updated2011-06-28 v1
- Checksum7F495D04A7585728
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP002656 EMBL· GenBank· DDBJ | AEB94512.1 EMBL· GenBank· DDBJ | Genomic DNA |