NAA40 contributes to colorectal cancer growth by controlling PRMT5 expression.
- AnnotationThe findings strengthen the importance of NAA40 to maintain colorectal cancer cell growth. We show that NAA40 oncogenic properties stimulate the global levels of H4R3me2s by transcriptionally activating PRMT5 methyltransferase which in turn modulates the expression of key downstream cancer-related genes.
- CategoriesFunction, Expression
- SourceGeneRif: 79829