F2W7D9 · F2W7D9_APLCA
- Protein5-HT2 receptor
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids992 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Cellular Component | synapse | |
Molecular Function | dopamine neurotransmitter receptor activity, coupled via Gi/Go | |
Molecular Function | G protein-coupled receptor activity | |
Biological Process | adenylate cyclase-activating adrenergic receptor signaling pathway |
Keywords
- Molecular function
Names & Taxonomy
Protein names
- Submitted names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Spiralia > Lophotrochozoa > Mollusca > Gastropoda > Heterobranchia > Euthyneura > Tectipleura > Aplysiida > Aplysioidea > Aplysiidae > Aplysia
Accessions
- Primary accessionF2W7D9
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 441-466 | Helical | ||||
Sequence: YTWSILMMAPLVVFGVAGNTLVILAI | ||||||
Transmembrane | 478-503 | Helical | ||||
Sequence: YFLLSLAVTDLLVSLIVMPFSIINVF | ||||||
Transmembrane | 509-537 | Helical | ||||
Sequence: FGLLLCDFFVTSDVLMCTSSILHLCTISL | ||||||
Transmembrane | 557-579 | Helical | ||||
Sequence: VLLKIVLVWTIALAITSPITVLG | ||||||
Transmembrane | 599-621 | Helical | ||||
Sequence: FVIYGSIFAFFLPLAIMILMYAL | ||||||
Transmembrane | 870-892 | Helical | ||||
Sequence: VLGVVFMIFVVCWAPFFTVNILT | ||||||
Transmembrane | 904-926 | Helical | ||||
Sequence: LITAFVWLGYVSSTLNPIIYTIF |
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for region, domain, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-67 | Disordered | ||||
Sequence: MSDNDPWSLRPPGLASAGREEGEGEDILGMNKSARNTGAGHRHRHNKHNQLAGALSEASADGAAGGG | ||||||
Domain | 458-923 | G-protein coupled receptors family 1 profile | ||||
Sequence: GNTLVILAISLEKRLQNVTNYFLLSLAVTDLLVSLIVMPFSIINVFTGRWLFGLLLCDFFVTSDVLMCTSSILHLCTISLERYIGIRYPLWTKNKSKRVVLLKIVLVWTIALAITSPITVLGVVRAQNVLVDDVCVVNNEHFVIYGSIFAFFLPLAIMILMYALTVRMLNKQARLCQTRRADDGEGEPMIRRSTSRRNWQGRRKFYGREVLSATPSCCDPRSGGGGGGGDSGGGSGGVLSFHQRYRPLGGGVSRHNTIPLYHNSHHHHHHHNHNHHNHQQQHHHRNHNSSYAHHNNYLPLDRHHQIERRETANCCGVGGVDWGGGGEPKRLRELVRKHHVAVKAANILLLKRDGQQQQQQQQQHHQQRGQGGVQGPGSSGHHGGHHRGSTSSSTNYSVRRDNSVRTEQKASKVLGVVFMIFVVCWAPFFTVNILTVLCTSCRFEPTLITAFVWLGYVSSTLNPIIY | ||||||
Region | 673-695 | Disordered | ||||
Sequence: SCCDPRSGGGGGGGDSGGGSGGV | ||||||
Compositional bias | 719-747 | Basic residues | ||||
Sequence: HNSHHHHHHHNHNHHNHQQQHHHRNHNSS | ||||||
Region | 719-752 | Disordered | ||||
Sequence: HNSHHHHHHHNHNHHNHQQQHHHRNHNSSYAHHN | ||||||
Compositional bias | 809-831 | Polar residues | ||||
Sequence: RDGQQQQQQQQQHHQQRGQGGVQ | ||||||
Region | 809-859 | Disordered | ||||
Sequence: RDGQQQQQQQQQHHQQRGQGGVQGPGSSGHHGGHHRGSTSSSTNYSVRRDN | ||||||
Compositional bias | 841-858 | Polar residues | ||||
Sequence: GHHRGSTSSSTNYSVRRD |
Sequence similarities
Belongs to the G-protein coupled receptor 1 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Protein family/group databases
Sequence
- Sequence statusComplete
- Length992
- Mass (Da)108,284
- Last updated2011-05-31 v1
- ChecksumB2AAC5C33C8CBAFD
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 719-747 | Basic residues | ||||
Sequence: HNSHHHHHHHNHNHHNHQQQHHHRNHNSS | ||||||
Compositional bias | 809-831 | Polar residues | ||||
Sequence: RDGQQQQQQQQQHHQQRGQGGVQ | ||||||
Compositional bias | 841-858 | Polar residues | ||||
Sequence: GHHRGSTSSSTNYSVRRD |
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
HM187583 EMBL· GenBank· DDBJ | AEA76356.1 EMBL· GenBank· DDBJ | mRNA |