F1Z3U2 · F1Z3U2_9SPHN

Function

function

Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site178
Active site204
Active site300

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionphosphorelay response regulator activity
Molecular Functionprotein-glutamate methylesterase activity
Molecular Functionprotein-glutamine glutaminase activity
Biological Processchemotaxis
Biological Processprotein deamination
Biological Processprotein demethylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein-glutamate methylesterase/protein-glutamine glutaminase
  • EC number

Gene names

    • Name
      cheB
    • ORF names
      Y88_1815

Organism names

Accessions

  • Primary accession
    F1Z3U2

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue574-aspartylphosphate

Post-translational modification

Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain6-123Response regulatory
Domain166-353CheB-type methylesterase

Domain

Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.

Sequence similarities

Belongs to the CheB family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    357
  • Mass (Da)
    38,068
  • Last updated
    2011-05-31 v1
  • Checksum
    9826F5D8DD960038
MGRKIRVLVVDDSASVRQTMTAILSADPEIEVIAAASDPFAAARYIKDELPDVVTLDVEMPRMDGITFLRKLMSQCPVPVVMCSSLTEEGSETLLQALEAGAVDVILKPRAGVADFLAEQNQRIRDVVKGAAHAKVSRRADRAPLRPEGKLTADAMLPPPIARAMSRTTEMVVCIGASTGGTEALREVLEALPANAPGIVVVQHMPEQFTRSFAARLNARCEVDVKEAEDGDTVMRGHVLIAPGGRHTLLARQGARYVVSVREGPLVSRHRPSVNVLFRSAAQWAGANAVGVIMTGMGDDGAQGLLEMRQAGARTIAQNEATSVVFGMPREAIALGAAERIVPLGAIAREMIQAGMR

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AEWJ01000013
EMBL· GenBank· DDBJ
EGD60734.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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