F1W2Z8 · F1W2Z8_9BURK

Function

function

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Fe2+ (UniProtKB | Rhea| CHEBI:29033 )

Note: Binds 1 Fe2+ ion.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site100Fe cation (UniProtKB | ChEBI)
Binding site142Fe cation (UniProtKB | ChEBI)
Active site143
Binding site146Fe cation (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionmetal ion binding
Molecular Functionpeptide deformylase activity
Biological Processtranslation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Peptide deformylase
  • EC number
  • Short names
    PDF
  • Alternative names
    • Polypeptide deformylase

Gene names

    • Name
      def
    • ORF names
      IMCC9480_789

Organism names

Accessions

  • Primary accession
    F1W2Z8

Proteomes

Family & Domains

Sequence similarities

Belongs to the polypeptide deformylase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    178
  • Mass (Da)
    19,859
  • Last updated
    2011-05-31 v1
  • Checksum
    F6F87DF92E645E0A
MTVREILKMGDPRLLRVAEPVTEFDTPAMRLLIADMFETMHAVNGAGLAAPQIGVNLQLVIYGSRNNVRYPEAPEVPETILINPVLTPLSDELVENWEGCLSVPGLRGVVPRWQALHYEGVDQFGAVISRDVDGFHARVVQHECDHLIGVLYPMRVTDFSRFGYTSVLFPELDGDEDD

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AEPR01000600
EMBL· GenBank· DDBJ
EGF30770.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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