F1VWI4 · F1VWI4_9BURK
- ProteinSuccinate dehydrogenase flavoprotein subunit
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids592 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- a quinone + succinate = a quinol + fumarate
Cofactor
Pathway
Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (bacterial route): step 1/1.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 19-24 | FAD (UniProtKB | ChEBI) | ||||
Sequence: GAGGSG | ||||||
Binding site | 42-57 | FAD (UniProtKB | ChEBI) | ||||
Sequence: SKVFPTRSHTVAAQGG | ||||||
Binding site | 226 | FAD (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 247 | substrate | ||||
Sequence: H | ||||||
Binding site | 259 | substrate | ||||
Sequence: T | ||||||
Active site | 291 | Proton acceptor | ||||
Sequence: R | ||||||
Binding site | 358 | substrate | ||||
Sequence: H | ||||||
Binding site | 392 | FAD (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 403 | substrate | ||||
Sequence: R | ||||||
Binding site | 408-409 | FAD (UniProtKB | ChEBI) | ||||
Sequence: SL |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | flavin adenine dinucleotide binding | |
Molecular Function | succinate dehydrogenase (quinone) activity | |
Biological Process | electron transport chain | |
Biological Process | tricarboxylic acid cycle |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSuccinate dehydrogenase flavoprotein subunit
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Oxalobacteraceae
Accessions
- Primary accessionF1VWI4
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Peripheral membrane protein
Membrane ; Peripheral membrane protein
Keywords
- Cellular component
PTM/Processing
Features
Showing features for modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Modified residue | 50 | Tele-8alpha-FAD histidine | ||||
Sequence: H |
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 14-409 | FAD-dependent oxidoreductase 2 FAD binding | ||||
Sequence: DAVIIGAGGSGMRASLQLAEAGLNVAVLSKVFPTRSHTVAAQGGIGASLGNMSEDSWFWHMFDTVKGGDYLGDQDAIEFMCREAPKVVYELEHFGMPFDRNPDGTIYQRPFGGHTANFGEKPVQRACAAADRTGHAMLHTLYQRNVRAKTHFFVEWMALDLIRDADGDVIGVVALEMETGECMILEAKTTIMATGGAGRIWAASTNAFINTGDGMGMAARAGLPLEDMEFWQFHPTGVAGAGVLITEGVRGEGGILINSEGERFMERYAPTLKDLAPRDFVSRSMDQEIKEGRGCGPNKDHVLLDLRHIGAETIQKRLPSILEIGHKFANVDATKEPIPVVPTIHYQMGGIPTNIHGQVVAPKNGNPNAVVNGLYAIGECACVSVHGANRLGTNSL | ||||||
Domain | 466-591 | Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal | ||||
Sequence: DIRAAMQRYCGVFRTDALLQSGYNAIMELDERRKNVSFKDKSKVFNTARVEALELDNMIEAAKATISSALARKESRGAHAQSDYETRDDANWMKHSLWYSEGNRLDYKPVVTKPLTVETFQPKART |
Sequence similarities
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length592
- Mass (Da)64,568
- Last updated2011-05-31 v1
- Checksum07311F50BCB353FE
Keywords
- Technical term