F1RBN2 · SPAG1_DANRE
- ProteinSperm-associated antigen 1A
- Genespag1a
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids427 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
May play a role in the cytoplasmic assembly and/or trafficking of the axonemal dynein arms.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | cytosol | |
Cellular Component | dynein axonemal particle | |
Biological Process | axonemal dynein complex assembly |
Names & Taxonomy
Protein names
- Recommended nameSperm-associated antigen 1A
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionF1RBN2
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Note: Colocalizes with tubulin.
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
Morpholino knockdown of the protein causes increase incidence of dorsal curvature and hydrocephalus.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000428751 | 1-427 | Sperm-associated antigen 1A | |||
Sequence: MSQQEVCPLNLFQSAQGTGRVCMRVCVCERGRELAVLYRAAMGNAQKKGPGYREGGGPNSQPGTPGRRRSHGLNNAANSKEVPGSSPAANGSLPAGKSQDEPQGPGSAGESCNLDAPCGALPPPLARLKNQGNMLFKNGQFGDALEKYTQAIDGCIEAGIDSPEDLCVLYSNRAACFLKDGNSADCIQDCTRALELHPFSLKPLLRRAMAYESLERYRKAYVDYKTVLQIDISVQAAHDSVHRITKMLIEQDGPDWREKLPEIPAVPLSAQQHRKEEPSAELLQARAERAEQEKARKAEARFTILKQEGNELVKNSQFQGASEKYSECLAIKPNECAIYTNRALCFLKLERFAEAKQDCDSALQMEPKNKKAFYRRALAHKGLKDYLSASTDLQEVLQLDPNVQEAEQELEMVTNLLRESLLANAQG |
Proteomic databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, repeat.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 46-113 | Disordered | ||||
Sequence: QKKGPGYREGGGPNSQPGTPGRRRSHGLNNAANSKEVPGSSPAANGSLPAGKSQDEPQGPGSAGESCN | ||||||
Compositional bias | 63-97 | Polar residues | ||||
Sequence: GTPGRRRSHGLNNAANSKEVPGSSPAANGSLPAGK | ||||||
Repeat | 125-158 | TPR 1 | ||||
Sequence: LARLKNQGNMLFKNGQFGDALEKYTQAIDGCIEA | ||||||
Repeat | 167-200 | TPR 2 | ||||
Sequence: CVLYSNRAACFLKDGNSADCIQDCTRALELHPFS | ||||||
Repeat | 202-234 | TPR 3 | ||||
Sequence: KPLLRRAMAYESLERYRKAYVDYKTVLQIDISV | ||||||
Repeat | 302-335 | TPR 4 | ||||
Sequence: FTILKQEGNELVKNSQFQGASEKYSECLAIKPNE | ||||||
Repeat | 336-369 | TPR 5 | ||||
Sequence: CAIYTNRALCFLKLERFAEAKQDCDSALQMEPKN | ||||||
Repeat | 371-403 | TPR 6 | ||||
Sequence: KAFYRRALAHKGLKDYLSASTDLQEVLQLDPNV |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length427
- Mass (Da)46,984
- Last updated2011-05-03 v1
- ChecksumAC631ED75F2C51E8
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A0H2UKG1 | A0A0H2UKG1_DANRE | spag1a | 386 |
Sequence caution
Features
Showing features for compositional bias, sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 63-97 | Polar residues | ||||
Sequence: GTPGRRRSHGLNNAANSKEVPGSSPAANGSLPAGK | ||||||
Sequence conflict | 105 | in Ref. 2; AAI39536 | ||||
Sequence: P → L |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FP236813 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
BC139535 EMBL· GenBank· DDBJ | AAI39536.1 EMBL· GenBank· DDBJ | mRNA | Different initiation |