F1QR77 · F1QR77_DANRE

Function

Catalytic activity

  • diphospho-myo-inositol polyphosphate + H2O = myo-inositol polyphosphate + phosphate.
    EC:3.6.1.52 (UniProtKB | ENZYME | Rhea)

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular Functionbis(5'-adenosyl)-hexaphosphatase activity
Molecular Functionbis(5'-adenosyl)-pentaphosphatase activity
Molecular Functiondiphosphoinositol-polyphosphate diphosphatase activity
Molecular Functionendopolyphosphatase activity
Biological Processadenosine 5'-(hexahydrogen pentaphosphate) catabolic process
Biological Processdiadenosine hexaphosphate catabolic process
Biological Processdiadenosine pentaphosphate catabolic process
Biological Processdiphosphoinositol polyphosphate metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    diphosphoinositol-polyphosphate diphosphatase
  • EC number

Gene names

    • Name
      nudt4a
    • Synonyms
      nudt4
      , sb:cb946
      , zgc:110482

Organism names

  • Taxonomic identifier
  • Strain
    • Tuebingen
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    F1QR77
  • Secondary accessions
    • A0A8M1P2C8

Proteomes

    • Identifier
    • Component
      Alternate scaffold 18, Chromosome 18

Organism-specific databases

Subcellular Location

Expression

Gene expression databases

Family & Domains

Features

Showing features for domain, compositional bias, region.

TypeIDPosition(s)Description
Domain61-187Nudix hydrolase
Compositional bias191-216Polar residues
Region191-225Disordered

Sequence similarities

Belongs to the Nudix hydrolase family. DIPP subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    225
  • Mass (Da)
    25,634
  • Last updated
    2018-06-20 v2
  • Checksum
    1026A59C6E96E9FE
MISLGNLGRLSALGLKGSCVARRIQKLGNREHLYSCFVRRKTHMMKFKPNQTRTYDGEGFKKRAACLCFKNDREDEVLLVSSSRHPDQWIVPGGGMEPEEEPGGAAVREVYEEAGVRGTLGRLLGVFENQDSKHRTYVYVLTVTETLEDWEDSVNIGRKRKWFKIDEAIRVLQCHKPFHAEYLRKLTPRCGPTNGNTQEPTMNTDDNASLRQTASHDCGLTRLHR

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
Q1L8L1Q1L8L1_DANREnudt4a226

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias191-216Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CR753897
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

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