F1QLR7 · F1QLR7_DANRE

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Features

Showing features for binding site, active site.

113821002003004005006007008009001,0001,1001,2001,300
Type
IDPosition(s)Description
Binding site1085-1093ATP (UniProtKB | ChEBI)
Binding site1111ATP (UniProtKB | ChEBI)
Binding site1158-1161ATP (UniProtKB | ChEBI)
Active site1205Proton acceptor
Binding site1209ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentbasal plasma membrane
Cellular Componentplasma membrane
Cellular Componentreceptor complex
Molecular FunctionATP binding
Molecular Functionhepatocyte growth factor receptor activity
Molecular Functionsemaphorin receptor activity
Biological Processaxon guidance
Biological Processcell migration
Biological Processcentral nervous system neuron differentiation
Biological Processcerebellar granule cell differentiation
Biological Processcerebellum development
Biological Processcerebellum morphogenesis
Biological Processcranial nerve formation
Biological Processexocrine pancreas development
Biological Processglial cell migration
Biological Processliver development
Biological Processmuscle cell migration
Biological Processnervous system development
Biological Processneuron differentiation
Biological Processneuron migration
Biological Processpancreas development
Biological Processpectoral fin development
Biological Processphagocytosis
Biological Processprotein phosphorylation
Biological Processspinal cord motor neuron differentiation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Hepatocyte growth factor receptor
  • EC number
  • Alternative names
    • HGF/SF receptor
    • Proto-oncogene c-Met
    • Scatter factor receptor
    • Tyrosine-protein kinase Met

Gene names

    • Name
      met
    • Synonyms
      c-met
      , cmet

Organism names

  • Taxonomic identifier
  • Strain
    • Tuebingen
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    F1QLR7
  • Secondary accessions
    • A0A8M2B9Z7

Proteomes

Organism-specific databases

Subcellular Location

Membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane932-954Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain, disulfide bond, modified residue.

Type
IDPosition(s)Description
Signal1-24
ChainPRO_500995414625-1382Hepatocyte growth factor receptor
Disulfide bond104↔155
Disulfide bond131↔139
Disulfide bond168↔171
Disulfide bond294↔359
Disulfide bond515↔533
Disulfide bond521↔558
Disulfide bond524↔542
Disulfide bond536↔548
Modified residue1235Phosphotyrosine; by autocatalysis
Modified residue1236Phosphotyrosine; by autocatalysis
Modified residue1350Phosphotyrosine; by autocatalysis
Modified residue1357Phosphotyrosine; by autocatalysis

Keywords

Proteomic databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain27-510Sema
Domain1079-1342Protein kinase

Sequence similarities

Belongs to the plexin family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,382
  • Mass (Da)
    154,185
  • Last updated
    2011-05-03 v1
  • Checksum
    B8BB057D013476C2
MTIHYSEAASILIILQSLWWGLNCQCEEPIESSKLDLSVTYDLPYFVSDTPIQKLLEINGTVYVGAVNRLYALSKDLKKKHEYKTGPVHEGPDCKTPTDQCSGCENKPRNINNTNMALLMETFYDLELFSCGSVGNGVCSRHVLEDGPLGAEVTCMYTKKNEGSSHGCPDCLAGPAGTQILNIMSGRVVRFFVANSEPLESNGPRLHHTISIRKMRETQDGFEFFSDQSYMDLAPSLRGNYPLHYVYSFQSGPYVYFLTVQREGGNSKAFHTRIVRMCSSDSEILRYVEMPFECIYSERRRKKRSAQVVFNVLQAAHVAKVGYDFQQEMGLKEGEDVLFAAFARSKPDSPEPTASSAVCLISITDINEFFKVFIQKGYTRKLHHFPGSEEKTFNQTFVGDSFSCGKHERGYRLEVTSTNPRRDYFHGRFRNVLLTSIAVVPIQNHTVVSLGTAEGRVIQVVVSRFGKTEPHVDFRLDTLPVSSEMALLSPQHHNGSLLLITGNKVSKLPVIGPGCEQLWTCSSCLLAPGFMGCGWCRTSNLCTRAPRCPQSQWIQDSCPLLITSISPSSAPLRGQTNITICGKNFGFNKKDRFDTKLIDVVVAGTKCKLERKDSNNNRLVCGLDHVNWSSVDSVVTVRSGKEQAQKDGFSFVNPVIIEIFPEFGPQSGGTMLTISGSFLDSGNVQTVTVGNATCVLQSVSATMLTCRTPPQPSPSQHKVQLHIDGVIFEAPVSYTYNKNPHISSVQPKHSFISGGSTVTVNGFYLHSALQPQMVLTAATEGKLFQVTCSHDEDKRNILCITPSLKGLSVQPPVATKMTFVLDGFSTDQYDLLYVEDPKFEEFQKPTVTPRGKKNILEIKVPPVNQEAVKNGEVLRVSNRTCESVTLVGNTLECTVPMELQTAAKELEVEWKQATSSVILGRVILAQDQDYRILITGGVCVSILLLLLIAVFVWIKRKKHINDLAKTMVWYDGRAHIPHLDMLANARSVSPTNEMVSHESVDYRTTLLEDQNLPLSQTESCRPHLYAHSHVDLSPMLGPMEGDLASPLLPSTAPIDLGSLHPELLKEVQHVVIAREDLLLHVNEIIGRGHFGCVFHGTLLEPDGQKQHCAIKSLNRITDIEEVSQFLKEGIIMKDFSHPNVLSLLGICLPSEGSPLVVLPYMKHGDLRNFIRDESHNPTVKDLMGFGLQVAKGMEYLASKKFVHRDLAARNCMLDESYTVKVADFGLARDVYDKEYYSVHNKHGVKLPVKWMALESLQTHKFTTKSDVWSFGVLLWELMTRGAPPYSDVNSFDITVFLLQGRRLLQPEFCPDALYNVMIECWHPKPERRPTFSELVSRISAIFSSFSGEHYILLNTTYVNIDKMTPYPSLISSQSNLDRDCCT

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q64GK4Q64GK4_DANREmet1382
A0A8M2BA12A0A8M2BA12_DANREmet1335

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CR848711
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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