F1QF86 · F1QF86_DANRE
- ProteinSerine/threonine-protein phosphatase
- Geneppp3ccb
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids506 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
Catalytic activity
- O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate
Cofactor
Protein has several cofactor binding sites:
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | calcineurin complex | |
Cellular Component | cytoplasm | |
Molecular Function | calmodulin binding | |
Molecular Function | calmodulin-dependent protein phosphatase activity | |
Molecular Function | metal ion binding | |
Molecular Function | myosin phosphatase activity | |
Biological Process | calcineurin-mediated signaling |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSerine/threonine-protein phosphatase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionF1QF86
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 144-149 | Serine/threonine specific protein phosphatases | ||||
Sequence: LRGNHE | ||||||
Region | 455-506 | Disordered | ||||
Sequence: PQHKIQSFEEARGLDRINERMPPRRDTKQPDGTANSINAANSPDKNGTNTQA | ||||||
Compositional bias | 462-481 | Basic and acidic residues | ||||
Sequence: FEEARGLDRINERMPPRRDT | ||||||
Compositional bias | 483-506 | Polar residues | ||||
Sequence: QPDGTANSINAANSPDKNGTNTQA |
Sequence similarities
Belongs to the PPP phosphatase family. PP-2B subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length506
- Mass (Da)57,514
- Last updated2011-05-03 v1
- ChecksumF34679B0D27A6F27
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8M2B1V9 | A0A8M2B1V9_DANRE | ppp3ccb | 511 | ||
A0A8M2B273 | A0A8M2B273_DANRE | ppp3ccb | 502 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 462-481 | Basic and acidic residues | ||||
Sequence: FEEARGLDRINERMPPRRDT | ||||||
Compositional bias | 483-506 | Polar residues | ||||
Sequence: QPDGTANSINAANSPDKNGTNTQA |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CR381599 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
CR450836 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |