F1NVK6 · TM237_CHICK

  • Protein
    Transmembrane protein 237
  • Gene
    TMEM237
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Component of the transition zone in primary cilia. Required for ciliogenesis (By similarity).

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentciliary transition zone
Cellular Componentmembrane
Biological Processcilium assembly
Biological Processregulation of Wnt signaling pathway

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Transmembrane protein 237

Gene names

    • Name
      TMEM237

Organism names

  • Taxonomic identifier
  • Strain
    • Red jungle fowl
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Galloanserae > Galliformes > Phasianidae > Phasianinae > Gallus

Accessions

  • Primary accession
    F1NVK6

Proteomes

Organism-specific databases

Subcellular Location

Membrane
; Multi-pass membrane protein
Note: Localizes to the transition zone.

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane213-233Helical
Transmembrane254-274Helical
Transmembrane288-308Helical
Transmembrane344-364Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004158301-394Transmembrane protein 237

Proteomic databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region1-135Disordered
Compositional bias25-39Basic and acidic residues
Compositional bias45-59Polar residues
Compositional bias80-96Polar residues

Sequence similarities

Belongs to the TMEM237 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    394
  • Mass (Da)
    44,406
  • Last updated
    2012-02-22 v2
  • Checksum
    D73C9F788C72B2EA
MGKKQVCPPRALPPVPSFCSADDIPLSRPKKRKPKGKTPLDDIVQATVRRQSESSEPLTPEPQDVPPQRKRKKKKVPPDSETSFTQQNTASLFQNGNGVDVPEAEETVVRKQRKRTKKARPAETHSSNELEVEEDDIIEDEHRRSPDQQPVFAAPTGISQPVSKVFVEKNRRFQAADRAELIKTTENINVLLDVKSSWTTRDVALSVHRSFRVIGLFTHGFLAGYAVWNIVVIYILAGNQLTTVSNLLQQYKMLAYPAQSLFYLLLSISTVSAFDRIDLAKASVALRGFLTLDPAALASFLYFTALILSLSQQMTCDRINLYTPPSENGSIWTAGMEEEILQPWIVVNLVVSILVGASWIFLSYRPELDHSEELMFHTEIEEFPQDEREMLKSQ

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias25-39Basic and acidic residues
Compositional bias45-59Polar residues
Compositional bias80-96Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AADN02019863
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Similar Proteins

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