F1MU47 · F1MU47_BOVIN
- Proteinsteroid 11beta-monooxygenase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids457 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- 21-hydroxyprogesterone + 2 H+ + O2 + 2 reduced [adrenodoxin] = corticosterone + H2O + 2 oxidized [adrenodoxin]This reaction proceeds in the forward direction.
Cofactor
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Molecular Function | corticosterone 18-monooxygenase activity | |
Molecular Function | heme binding | |
Molecular Function | iron ion binding | |
Molecular Function | steroid 11-beta-monooxygenase activity | |
Biological Process | aldosterone biosynthetic process | |
Biological Process | cellular response to peptide hormone stimulus | |
Biological Process | cholesterol metabolic process | |
Biological Process | cortisol metabolic process | |
Biological Process | glucocorticoid biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namesteroid 11beta-monooxygenase
- EC number
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos
Accessions
- Primary accessionF1MU47
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Peripheral membrane protein
Mitochondrion inner membrane ; Peripheral membrane protein
Keywords
- Cellular component
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 303-331 | Disordered | ||||
Sequence: VDTVRPARSPSHRAGSSPASRQPPPRANA |
Sequence similarities
Belongs to the cytochrome P450 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length457
- Mass (Da)52,567
- Last updated2019-04-10 v3
- Checksum85B0053CF58DEF34
Keywords
- Technical term