F1D8S6 · F1D8S6_HUMAN

  • Protein
    Retinoic acid receptor beta
  • Gene
    NR1B2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    5/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleoplasm
Cellular Componenttranscription regulator complex
Molecular Functionheterocyclic compound binding
Molecular Functionnuclear glucocorticoid receptor binding
Molecular Functionnuclear receptor activity
Molecular Functionnuclear retinoid X receptor binding
Molecular Functionprotein-containing complex binding
Molecular FunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding
Molecular Functionzinc ion binding
Biological Processapoptotic process
Biological Processcellular response to corticotropin-releasing hormone stimulus
Biological Processembryonic eye morphogenesis
Biological Processembryonic hindlimb morphogenesis
Biological Processglandular epithelial cell development
Biological Processgrowth plate cartilage development
Biological Processmulticellular organism growth
Biological Processnegative regulation of chondrocyte differentiation
Biological Processnegative regulation of stem cell proliferation
Biological Processnegative regulation of transcription by RNA polymerase II
Biological Processneural precursor cell proliferation
Biological Processneurogenesis
Biological Processpositive regulation of apoptotic process
Biological Processpositive regulation of transcription by RNA polymerase II
Biological Processregulation of myelination
Biological Processretinoic acid receptor signaling pathway
Biological Processstem cell proliferation
Biological Processstriatum development
Biological Processureteric bud development
Biological Processventricular cardiac muscle cell differentiation

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Retinoic acid receptor beta
  • Alternative names
    • Nuclear receptor subfamily 1 group B member 2

Gene names

    • Name
      NR1B2
    • Synonyms
      RARB
    • ORF names
      hCG_26863

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    F1D8S6

Organism-specific databases

Subcellular Location

Keywords

  • Cellular component

Disease & Variants

Organism-specific databases

Expression

Gene expression databases

Structure

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias48-65Polar residues
Region48-72Disordered
Domain78-153Nuclear receptor
Domain176-410NR LBD
Region408-448Disordered
Compositional bias413-448Polar residues

Sequence similarities

Belongs to the nuclear hormone receptor family. NR1 subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    448
  • Mass (Da)
    50,344
  • Last updated
    2011-05-03 v1
  • Checksum
    844A298AD32F46A8
MFDCMDVLSVSPGQILDFYTASPSSCMLQEKALKACFSGLTQTEWQHRHTAQSIETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKETSKQECTESYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPSSSGNTAEHSPSISPSSVENSGVSQSPLVQ

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias48-65Polar residues
Compositional bias413-448Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HQ692864
EMBL· GenBank· DDBJ
ADZ17375.1
EMBL· GenBank· DDBJ
mRNA
CH471055
EMBL· GenBank· DDBJ
EAW64354.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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