F0VIJ6 · F0VIJ6_NEOCL
- ProteinGlutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids697 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
Catalytic activity
- ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H+ + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | glutamyl-tRNA(Gln) amidotransferase complex | |
Cellular Component | mitochondrion | |
Molecular Function | ATP binding | |
Molecular Function | glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity | |
Biological Process | glutaminyl-tRNAGln biosynthesis via transamidation | |
Biological Process | mitochondrial translation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial
- EC number
- Short namesGlu-AdT subunit B
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Sar > Alveolata > Apicomplexa > Conoidasida > Coccidia > Eucoccidiorida > Eimeriorina > Sarcocystidae > Neospora
Accessions
- Primary accessionF0VIJ6
Proteomes
Organism-specific databases
Subcellular Location
Interaction
Subunit
Heterotrimer of A, B and C subunits.
Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits.
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 99-126 | Basic and acidic residues | ||||
Sequence: KMLHASGKTEHLATLDRSRGRGASARET | ||||||
Region | 99-180 | Disordered | ||||
Sequence: KMLHASGKTEHLATLDRSRGRGASARETRSQTRTDASAQAGRHGHGNGGRDGGRSGDAPRGDTQEPAATQEPAATQEPEATP | ||||||
Region | 286-307 | Disordered | ||||
Sequence: ALRKEPLAPPTPPTDAEDDPDS | ||||||
Domain | 407-674 | Asn/Gln amidotransferase | ||||
Sequence: PFFEAAVAAGAPPGPAASWLLNEVAGWRRRLSLPSRLDTATEKPPSRGISIDAPSEAVLEGERDERISEGTEARIDAAPESRREQPGGSARERKETHGDARAKPTSKRAPPLPLKALKLTPAKLAELLLLIDRGVVTHNTAKHLLPDLLLSWDGSVADLVAYRAQEVRNEDIEMHPSPNPRQQRHPAGSFLRHEAPGSTAAAGMAIEAHAREILAEHPEILSRFQSGMRNMADFVVGRILKRSKAPHDGAFGTQPVPQEIKAAVVRVM | ||||||
Region | 442-518 | Disordered | ||||
Sequence: RLDTATEKPPSRGISIDAPSEAVLEGERDERISEGTEARIDAAPESRREQPGGSARERKETHGDARAKPTSKRAPPL | ||||||
Compositional bias | 463-510 | Basic and acidic residues | ||||
Sequence: AVLEGERDERISEGTEARIDAAPESRREQPGGSARERKETHGDARAKP |
Sequence similarities
Belongs to the GatB/GatE family. GatB subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length697
- Mass (Da)76,043
- Last updated2011-05-03 v1
- ChecksumE91F0BE9302C00F5
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 99-126 | Basic and acidic residues | ||||
Sequence: KMLHASGKTEHLATLDRSRGRGASARET | ||||||
Compositional bias | 463-510 | Basic and acidic residues | ||||
Sequence: AVLEGERDERISEGTEARIDAAPESRREQPGGSARERKETHGDARAKP |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FR823390 EMBL· GenBank· DDBJ | CBZ53557.1 EMBL· GenBank· DDBJ | Genomic DNA |