F0VGU5 · F0VGU5_NEOCL

Function

Catalytic activity

  • Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.
    EC:5.6.2.4 (UniProtKB | ENZYME | Rhea)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentchromosome
Cellular Componentcytoplasm
Cellular Componentmembrane
Molecular Function3'-5' DNA helicase activity
Molecular FunctionATP binding
Molecular Functionfour-way junction helicase activity
Molecular Functionhydrolase activity
Molecular Functionnucleic acid binding
Biological ProcessDNA unwinding involved in DNA replication
Biological Processdouble-strand break repair via homologous recombination

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA 3'-5' helicase
  • EC number

Gene names

    • ORF names
      NCLIV_027280

Organism names

  • Taxonomic identifier
  • Strain
    • Liverpool
  • Taxonomic lineage
    Eukaryota > Sar > Alveolata > Apicomplexa > Conoidasida > Coccidia > Eucoccidiorida > Eimeriorina > Sarcocystidae > Neospora

Accessions

  • Primary accession
    F0VGU5

Proteomes

Organism-specific databases

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane128-149Helical

Keywords

  • Cellular component

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region1-78Disordered
Compositional bias7-21Basic and acidic residues
Compositional bias44-77Basic and acidic residues
Domain105-296Helicase ATP-binding
Region320-343Disordered
Compositional bias327-343Acidic residues
Domain346-498Helicase C-terminal
Compositional bias491-512Basic and acidic residues
Region491-528Disordered
Region566-648Disordered
Compositional bias587-601Basic and acidic residues
Compositional bias662-678Basic and acidic residues
Region662-687Disordered
Compositional bias906-920Basic and acidic residues
Region906-1027Disordered
Compositional bias979-1005Polar residues

Sequence similarities

Belongs to the helicase family. RecQ subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,027
  • Mass (Da)
    110,874
  • Last updated
    2011-05-03 v1
  • Checksum
    5568AC8F76A3F345
MVTNDAEGGMEKKEERDGKPPLGGNTDSLKLREAAGVAGPLTRKRPESETDRHACFFEKREKDGAEGDGEGAARPGKSLRDESLLQALKNAFGYSAFREGQEQAVRAILEGKDALVIMPTGGGKSLTYLLPGLLLPGLVIIVSPLLALMDDQSSPFSGGASRSSLSCLASSVSRGKYKFLFVTPEQVSSPTFQRVLGQLEARRRGVGIGEETKENRRNEEANGNRSQGVALIAVDEAHCISTWGHDFRRSYRQVERQNLSVLRTILPETPLLACTATATPAVCADIQTSLALRDAVRVGLSFDRKNIFYEVRMKRRLGPRPVEADDEEAALEGDPATAAEEEEDWTLEDMGAEVASRHRGECGIVYCFKKATCDSVATALRRKGIPAQAYHAGLSDKVRCELQRAWMTGKILVLVATVAFGLGVDNPNVRFVFHHSLPKTMEGYYQESGRCGRDGRPAHALLYYSPRNFESLRYIMDYTFSQLKLYAKGEPKGRARPQKGTGNRRGGEAKPEEESEETAETVDDHKARLEHMERRYRKDLESLKEVRQYCEETVCRRARILNFFGESLPPRRSSGPGPSGRRGSGEAQQGTERKRNREATEQDVTSCPGGVKRERKDQLVSAESPEGTPSSGPSSPRPPGGLCVGVSPSERATPCMNCREAEAGKREVERKNHSHGEEGASDLSPVSAGISSADAWRCCDLCEQREAEKANGRGSLGKALSTAAPSARLLASLASRGCTRVSSAARPARSFPGGGMAAVVGEDEGGALACGTLEFEKNDCSDDESRGESGWYGSKGSFRESAHLRRTVPGAWCPGSSALSRGPGAALGRGKGTDQFRRGISIGAGGRGRVVYHTSAESATARQSDGKIFHGAQGSTCAGSRSERVSDAIRAKGIRAVMEELERQEQLAEEADEMEGPKAQSRFFRQRFSAMKQRPASEAETHDPSSFSSRLPFPRPRPASLASTSGDRASELARTAASPSAVGRTNPPARSPTFVRASTLARDLSKSSAGKAAPQLRSGLCRPRGKG

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias7-21Basic and acidic residues
Compositional bias44-77Basic and acidic residues
Compositional bias327-343Acidic residues
Compositional bias491-512Basic and acidic residues
Compositional bias587-601Basic and acidic residues
Compositional bias662-678Basic and acidic residues
Compositional bias906-920Basic and acidic residues
Compositional bias979-1005Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FR823389
EMBL· GenBank· DDBJ
CBZ52939.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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