F0VGU5 · F0VGU5_NEOCL
- ProteinDNA 3'-5' helicase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1027 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | chromosome | |
Cellular Component | cytoplasm | |
Cellular Component | membrane | |
Molecular Function | 3'-5' DNA helicase activity | |
Molecular Function | ATP binding | |
Molecular Function | four-way junction helicase activity | |
Molecular Function | hydrolase activity | |
Molecular Function | nucleic acid binding | |
Biological Process | DNA unwinding involved in DNA replication | |
Biological Process | double-strand break repair via homologous recombination |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA 3'-5' helicase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Sar > Alveolata > Apicomplexa > Conoidasida > Coccidia > Eucoccidiorida > Eimeriorina > Sarcocystidae > Neospora
Accessions
- Primary accessionF0VGU5
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 128-149 | Helical | ||||
Sequence: YLLPGLLLPGLVIIVSPLLALM |
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-78 | Disordered | ||||
Sequence: MVTNDAEGGMEKKEERDGKPPLGGNTDSLKLREAAGVAGPLTRKRPESETDRHACFFEKREKDGAEGDGEGAARPGKS | ||||||
Compositional bias | 7-21 | Basic and acidic residues | ||||
Sequence: EGGMEKKEERDGKPP | ||||||
Compositional bias | 44-77 | Basic and acidic residues | ||||
Sequence: KRPESETDRHACFFEKREKDGAEGDGEGAARPGK | ||||||
Domain | 105-296 | Helicase ATP-binding | ||||
Sequence: VRAILEGKDALVIMPTGGGKSLTYLLPGLLLPGLVIIVSPLLALMDDQSSPFSGGASRSSLSCLASSVSRGKYKFLFVTPEQVSSPTFQRVLGQLEARRRGVGIGEETKENRRNEEANGNRSQGVALIAVDEAHCISTWGHDFRRSYRQVERQNLSVLRTILPETPLLACTATATPAVCADIQTSLALRDAV | ||||||
Region | 320-343 | Disordered | ||||
Sequence: RPVEADDEEAALEGDPATAAEEEE | ||||||
Compositional bias | 327-343 | Acidic residues | ||||
Sequence: EEAALEGDPATAAEEEE | ||||||
Domain | 346-498 | Helicase C-terminal | ||||
Sequence: TLEDMGAEVASRHRGECGIVYCFKKATCDSVATALRRKGIPAQAYHAGLSDKVRCELQRAWMTGKILVLVATVAFGLGVDNPNVRFVFHHSLPKTMEGYYQESGRCGRDGRPAHALLYYSPRNFESLRYIMDYTFSQLKLYAKGEPKGRARPQ | ||||||
Compositional bias | 491-512 | Basic and acidic residues | ||||
Sequence: PKGRARPQKGTGNRRGGEAKPE | ||||||
Region | 491-528 | Disordered | ||||
Sequence: PKGRARPQKGTGNRRGGEAKPEEESEETAETVDDHKAR | ||||||
Region | 566-648 | Disordered | ||||
Sequence: ESLPPRRSSGPGPSGRRGSGEAQQGTERKRNREATEQDVTSCPGGVKRERKDQLVSAESPEGTPSSGPSSPRPPGGLCVGVSP | ||||||
Compositional bias | 587-601 | Basic and acidic residues | ||||
Sequence: AQQGTERKRNREATE | ||||||
Compositional bias | 662-678 | Basic and acidic residues | ||||
Sequence: EAGKREVERKNHSHGEE | ||||||
Region | 662-687 | Disordered | ||||
Sequence: EAGKREVERKNHSHGEEGASDLSPVS | ||||||
Compositional bias | 906-920 | Basic and acidic residues | ||||
Sequence: QLAEEADEMEGPKAQ | ||||||
Region | 906-1027 | Disordered | ||||
Sequence: QLAEEADEMEGPKAQSRFFRQRFSAMKQRPASEAETHDPSSFSSRLPFPRPRPASLASTSGDRASELARTAASPSAVGRTNPPARSPTFVRASTLARDLSKSSAGKAAPQLRSGLCRPRGKG | ||||||
Compositional bias | 979-1005 | Polar residues | ||||
Sequence: PSAVGRTNPPARSPTFVRASTLARDLS |
Sequence similarities
Belongs to the helicase family. RecQ subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,027
- Mass (Da)110,874
- Last updated2011-05-03 v1
- Checksum5568AC8F76A3F345
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 7-21 | Basic and acidic residues | ||||
Sequence: EGGMEKKEERDGKPP | ||||||
Compositional bias | 44-77 | Basic and acidic residues | ||||
Sequence: KRPESETDRHACFFEKREKDGAEGDGEGAARPGK | ||||||
Compositional bias | 327-343 | Acidic residues | ||||
Sequence: EEAALEGDPATAAEEEE | ||||||
Compositional bias | 491-512 | Basic and acidic residues | ||||
Sequence: PKGRARPQKGTGNRRGGEAKPE | ||||||
Compositional bias | 587-601 | Basic and acidic residues | ||||
Sequence: AQQGTERKRNREATE | ||||||
Compositional bias | 662-678 | Basic and acidic residues | ||||
Sequence: EAGKREVERKNHSHGEE | ||||||
Compositional bias | 906-920 | Basic and acidic residues | ||||
Sequence: QLAEEADEMEGPKAQ | ||||||
Compositional bias | 979-1005 | Polar residues | ||||
Sequence: PSAVGRTNPPARSPTFVRASTLARDLS |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FR823389 EMBL· GenBank· DDBJ | CBZ52939.1 EMBL· GenBank· DDBJ | Genomic DNA |