F0VG41 · F0VG41_NEOCL
- ProteinAdenylosuccinate lyase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids405 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate
Pathway
Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2.
Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity | |
Molecular Function | N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity | |
Biological Process | 'de novo' AMP biosynthetic process | |
Biological Process | 'de novo' IMP biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAdenylosuccinate lyase
- EC number
- Short namesASL
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Sar > Alveolata > Apicomplexa > Conoidasida > Coccidia > Eucoccidiorida > Eimeriorina > Sarcocystidae > Neospora
Accessions
- Primary accessionF0VG41
Proteomes
Organism-specific databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 4-242 | Fumarate lyase N-terminal | ||||
Sequence: FSMEDALKVKEVEKKTNHDLKAVEYVLKEKLESTEVTADLSAFTHFGCTSEDVNNLAFAICFKEAVERQLLPAMESLAEALHARAVECADVPLLSLTHGQPATPTTFGKEIANFEWRVRNALKRVREVDFRGKYNGAVGNFNALVVADARVAWPVVARDFVESMGLVYQPYSTQIEQHDWLAELCDAFARFNSILLDFDRDMWLYISRDLLKLRVVAGEVGSSTMPHKVNPIDFENSEG | ||||||
Domain | 261-377 | Adenylosuccinate lyase PurB C-terminal | ||||
Sequence: SRMQRDLSDSTVLRNVGVAFGHCLVAYESTKKGLGRVDVNRAAMLRELENHWAVLGEPMQTVLRKRGVRNAYEKLKSATRGQAIDKERMQDIVEACGADLLPEDVDALRSLTPATYT |
Sequence similarities
Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length405
- Mass (Da)45,330
- Last updated2011-05-03 v1
- ChecksumED18A83937D59978
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FR823389 EMBL· GenBank· DDBJ | CBZ52685.1 EMBL· GenBank· DDBJ | Genomic DNA |