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F0V1K3 · F0V1K3_MYCS3

Function

function

Catalyzes the reversible phosphorylation of UMP to UDP.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Activity regulation

Inhibited by UTP.

Pathway

Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site11-14ATP (UniProtKB | ChEBI)
Binding site51UMP (UniProtKB | ChEBI)
Binding site52ATP (UniProtKB | ChEBI)
Binding site56ATP (UniProtKB | ChEBI)
Binding site71UMP (UniProtKB | ChEBI)
Binding site132-139UMP (UniProtKB | ChEBI)
Binding site166ATP (UniProtKB | ChEBI)
Binding site169ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionUMP kinase activity
Biological Process'de novo' CTP biosynthetic process
Biological Processphosphorylation
Biological ProcessUDP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Uridylate kinase
  • EC number
  • Short names
    UK
  • Alternative names
    • Uridine monophosphate kinase
      (UMP kinase
      ; UMPK
      )

Gene names

    • Name
      pyrH
    • ORF names
      MSUIS_04410

Organism names

Accessions

  • Primary accession
    F0V1K3

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homohexamer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain7-214Aspartate/glutamate/uridylate kinase

Sequence similarities

Belongs to the UMP kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    235
  • Mass (Da)
    25,992
  • Last updated
    2011-05-03 v1
  • MD5 Checksum
    B134E5B614A3672F245016DB3A344C36
MSVKKERILLKFSGGALKGKGEIYSEEKLIALASQVKELSKSYEIGIVIGGGNIWRGKEEKIDLLSAVQADYVGMMATIMNSYVFKETLESIGVKSRLYSALAVERIVEDYSLSKIEEDLSSGRVIIFGGGLGEPRFSTDSAAIMRGIEIGAKKILIGKDGVEGVYNKDPNIYEDAVFYGQLSYDRIISENIKVFDHSALNLAKENKLHFLIFNQEVENSFIKSLNGGIRVSEIF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FQ790233
EMBL· GenBank· DDBJ
CBZ40534.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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