F0NH04 · F0NH04_SULIR

Function

Catalytic activity

  • hydrolysis of (1->4)-alpha-D-glucosidic linkage in 4-alpha-D-[(1->4)-alpha-D-glucanosyl]n trehalose to yield trehalose and (1->4)-alpha-D-glucan.
    EC:3.2.1.141 (UniProtKB | ENZYME | Rhea)

Pathway

Glycan biosynthesis; trehalose biosynthesis.

Features

Showing features for binding site, active site, site.

156150100150200250300350400450500550
TypeIDPosition(s)Description
Binding site253-258substrate
Active site255Nucleophile
Active site286Proton donor
Binding site311-315substrate
Binding site379-384substrate
Site380Transition state stabilizer

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular Function4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity
Biological Processtrehalose biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Malto-oligosyltrehalose trehalohydrolase
  • EC number
  • Short names
    MTHase
  • Alternative names
    • 4-alpha-D-((1->4)-alpha-D-glucano)trehalose trehalohydrolase
    • Maltooligosyl trehalose trehalohydrolase

Gene names

    • Ordered locus names
      SiRe_0486

Organism names

Accessions

  • Primary accession
    F0NH04

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain109-487Glycosyl hydrolase family 13 catalytic

Sequence similarities

Belongs to the glycosyl hydrolase 13 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    561
  • Mass (Da)
    64,309
  • Last updated
    2011-05-03 v1
  • Checksum
    935EAD9AC4D3D97F
MAFGYRLDRNGVTFNLWAPYQRNVKLKILNKGIYEMERDEKGYFTITLNNVKVGDRYKYILDDGSEVPDPASRYQPEGVHGHSEIISLDFKGDDENGVKVKREDLIIYELHTSTFTSEGTFEGVIKKLDYLKELGVTAIEIMPIAQFPGKKDWGYDGVYLYAVQNSYGGPIGFRNLVNEAHKLGLAIILDVVYNHVGPEGNYMAKLGPYFSEKYKTPWGLAFNFDDAGSDEVRKFILENVEYWINEFHVDGFRLDAVHAIIDNSPKHILEDIADVVHKYGKIVITESDLNDPRVVNPKEKCGYNTDAQWVDDFHHAIHAFLTGERQGYYSDFGSLDDIVKSYKEVFVYDGKYSNFRRKTHGKPVGDLDGCKFVVYIQNHDQVGNRGGGERLIKLVDKESYKIAVALYMLSPYIPMIFMGEEYGEENPFYYFSDFSDPKLIQGVREGRKRDNGQETDPQSDSTFNASKLSWKVNDDILSFYKTLIKIRREYGLACNRKLTVENGNHWLTVKGNGYLVVYVFSQSIIEMKYRGTLVLSSNNSFPSQIAENKYELEKGFALYKL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP002425
EMBL· GenBank· DDBJ
ADX84572.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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