F0M1A9 · F0M1A9_PSEPM

Function

function

Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site43Zn2+ (UniProtKB | ChEBI)
Binding site43-46L-cysteinyl-5'-AMP (UniProtKB | ChEBI)
Binding site58L-cysteinyl-5'-AMP (UniProtKB | ChEBI)
Binding site81-83L-cysteinyl-5'-AMP (UniProtKB | ChEBI)
Binding site240L-cysteinyl-5'-AMP (UniProtKB | ChEBI)
Binding site244Zn2+ (UniProtKB | ChEBI)
Binding site262-264L-cysteinyl-5'-AMP (UniProtKB | ChEBI)
Binding site269Zn2+ (UniProtKB | ChEBI)
Binding site295L-cysteinyl-5'-AMP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionaminoacyl-tRNA ligase activity
Molecular FunctionATP binding
Molecular Functioncysteine-glucosaminylinositol ligase activity
Molecular Functionzinc ion binding
Biological Processmycothiol biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase
  • EC number
  • Short names
    L-Cys:GlcN-Ins ligase
  • Alternative names
    • Mycothiol ligase
      (MSH ligase
      )

Gene names

    • Name
      mshC
    • Ordered locus names
      Asphe3_18930

Organism names

Accessions

  • Primary accession
    F0M1A9

Proteomes

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, motif.

TypeIDPosition(s)Description
Domain34-349tRNA synthetases class I catalytic
Motif45-55'HIGH' region
Motif199-204'ERGGDP' region
Motif301-305'KMSKS' region

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    425
  • Mass (Da)
    45,338
  • Last updated
    2011-05-03 v1
  • Checksum
    FCA0EE1EF1513148
MKSWTSRPVPALPGNMPAIRLYDTAAGREVALEQENHPSMYVCGITPYDATHMGHASSYVAFDLLNRAWRDAGQEVAYVQNVTDVDDPLLERATATGVDWRDLAAGQIELFQTDMEALNVLPPDHYVGAVESIGLIVPEVERLVSLGLAYKVDGTNGEPDGDVYYDVEAAGKQSVAPDAWTLGCISGLNESEMLELFAERGGDPGRAGKRQALDPLLWRVEREGEPSWPGGSLGPGRPGWHIECTVIAQKYLPQPFTVQGGGSDLIFPHHEMGAGHAYSLAGVPLARHYAHAGMVGLDGEKMSKSKGNLVLVSKLRAAGEDPAAIRLGILAHHYRSDWSWTDHGFEDAKAILASWRQALPHAPAGSAAPLVAAMREALAADLNAPAAVAAVNRWAEQALSDGGPASPADQAMVRDAVDALLGVVL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP002379
EMBL· GenBank· DDBJ
ADX73048.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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