F0EUP9 · F0EUP9_HAEPA

Function

function

Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.
Metabolic intermediate biosynthesis; prephenate biosynthesis; prephenate from chorismate: step 1/1.

Features

Showing features for binding site, site.

TypeIDPosition(s)Description
Binding site9substrate
Binding site26substrate
Binding site37substrate
Binding site46substrate
Binding site50substrate
Binding site84substrate
Binding site88substrate
Site278Essential for prephenate dehydratase activity

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionchorismate mutase activity
Molecular Functionprephenate dehydratase activity
Biological Processchorismate metabolic process
Biological ProcessL-phenylalanine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Bifunctional chorismate mutase/prephenate dehydratase
  • EC number
  • Alternative names
    • Chorismate mutase-prephenate dehydratase
    • p-protein

Gene names

    • Name
      pheA
    • ORF names
      HMPREF9417_1601

Organism names

Accessions

  • Primary accession
    F0EUP9

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain, coiled coil.

TypeIDPosition(s)Description
Domain1-92Chorismate mutase
Coiled coil37-64
Domain105-285Prephenate dehydratase
Domain299-376ACT

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    385
  • Mass (Da)
    43,971
  • Last updated
    2011-05-03 v1
  • Checksum
    5FBCDE93FEE796C5
MALDLSEIRQQITQIDRSLLKLLSERHRLAYDVVRSKEVTQKALRDLEREQQLLQELVQFAESQNYQLEPQYITSVFQKIIEDSVLTQQVYLQKKLNEQREETLHIAFLGKRGSYSNLAARNYAARYHQQFAEISCDSFAQIFEKVESGEADYGVLPLENTTSGAINEVYDLLQHTTLSLVGELAYPIKHCVLVNEQDDLSKIDTLYSHPQVIQQCSQFIQSLERVHIEFCESSSHAMQLVASLNKPNIAALGNEDGGKLYGLHVLKHNIANQENNITRFIVVAKQAREVSPQIHTKTLLLMTTSQQAGSLVDALLVFKKHGINMTKLESRPIYGKPWEEMFYLEIEGNIHHPDTQIALEELKQFSNYLKVLGCYPSEIVKPAKV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AEWU01000019
EMBL· GenBank· DDBJ
EGC71769.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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