F0EF89 · F0EF89_ENTCA
- Protein6-O-methylguanine DNA methyltransferase, DNA binding domain protein
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids354 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
Catalytic activity
- a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] = a thymidine in DNA + S-methyl-L-cysteinyl-[protein]
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 37 | Nucleophile; methyl group acceptor from methylphosphotriester | |||
Binding site | 37 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 41 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 68 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 71 | Zn2+ (UniProtKB | ChEBI) | |||
Active site | 318 | Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | DNA-binding transcription factor activity | |
Molecular Function | methylated-DNA-[protein]-cysteine S-methyltransferase activity | |
Molecular Function | sequence-specific DNA binding | |
Molecular Function | zinc ion binding | |
Biological Process | DNA repair | |
Biological Process | methylation |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Enterococcaceae > Enterococcus
Accessions
- Primary accessionF0EF89
Proteomes
Structure
Sequence
- Sequence statusComplete
- Length354
- Mass (Da)40,104
- Last updated2011-05-03 v1
- ChecksumD1F179FA0AF94B1C
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AEWT01000002 EMBL· GenBank· DDBJ | EGC71014.1 EMBL· GenBank· DDBJ | Genomic DNA |