E9RHM9 · E9RHM9_9HEXA

  • Protein
    DNA polymerase
  • Gene
    DPD1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentdelta DNA polymerase complex
Molecular Function3'-5'-DNA exonuclease activity
Molecular Function4 iron, 4 sulfur cluster binding
Molecular FunctionDNA binding
Molecular FunctionDNA-directed DNA polymerase activity
Molecular Functionmetal ion binding
Molecular Functionnucleotide binding
Biological Processbase-excision repair, gap-filling
Biological ProcessDNA replication proofreading
Biological Processnucleotide-excision repair, DNA gap filling

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA polymerase
  • EC number

Gene names

    • Name
      DPD1

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 54
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Diplura > Rhabdura > Campodeoidea > Campodeidae > Lepidocampa

Accessions

  • Primary accession
    E9RHM9

Subcellular Location

Keywords

  • Cellular component

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias1-28Basic and acidic residues
Region1-73Disordered
Compositional bias39-57Acidic residues
Compositional bias58-73Basic and acidic residues
Domain232-472DNA-directed DNA polymerase family B exonuclease
Domain536-966DNA-directed DNA polymerase family B multifunctional
Domain1005-1074C4-type zinc-finger of DNA polymerase delta

Sequence similarities

Belongs to the DNA polymerase type-B family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,096
  • Mass (Da)
    125,123
  • Last updated
    2011-05-03 v1
  • Checksum
    3676FB5E9014078B
MNRKRGNFGKKPDGPGAKRQHAEDDDDLSYVFSSENDFDSQETLEEMDIDSQETLDEEAPDLEHSTAKWSRDPCPNFDPKEDNLLFQEMDIDVYTGFPMRGMPGLKVGSVPIVRLYGVTKQGNSICCHVHGFTPYFYVLLPDNFDNTHIPDFKDCLNRAMLNDLRRGKDDIPEPIISMEICDKQSIMYYQGSSVAKFLRIKVALPRLIAGTKRLLEKGDGVPQQFRQHIFRPFEANIDFETRFMVDKDLVGCAWVEIPKKAWRRRTQEGVGDGRCISRCQLEIDVSHERLICYAPEEEWSEIAPFRILSFDIECAGRKGIFPEAEKDPVIQIASMLQIQGQEEPMIRTVFTLNSCAPIVGSVVRSFNDEKELLEKWAEFVRQVDPDLITGYNINNFDLPYLLNRAKCLGSKHFSFLGRVIQSRSVVHDVTLQSKQMGRRENKSINIEGRVPFDLLLVLLRDYKLRSYTLNSVSFHFLQEQKEDVHHSIISDLHHGNAQTRRRLAIYCLKDAYLPLRLLDKLMCIINYMEMARVTGVPLSSLLTRGQQVKVMSQILRKAKTQNLIVPTYQSKGSDEQFEGATVIEPVKGYYNVPIATLDFSSLYPSIMMAHNLCYTTLVRPGLDKNLNPTDYIRTPSGNLFVKSALRKGLLPDILENLLSARKKAKDDLKKETDPFKRKVLDGRQLALKISANSVYGFTGAQVGKLPCLEISQSVTAFGRTMIEFTKKEVEERYNRSQGAEHDAQVIYGDTDSVMVKFGVQTVKEAMALGKEAAEYVSAKFVQPIRLEFEKVYFPYLLINKKRYAGLYFTRPEIHDKMDCKGIETVRRDNCPLVAKLITTCLEKILIDRDPNGAKTHAQQVISDLLCNRVDISQLVITKELTKTDKEYAAKQAHVELANKMRKRDAGTAPKLGDRVPYVIVNATKGTPAYQKAEDPIYVLENNIPIDCVYYLENQLAKPLLRIFEPILGESKAESELLRGDHTRTKIVVTSKVGAMAAFTRRRAACIGCKAMLKDERDAVCPHCKEGEVYQREIASMRVLQERFCRLWTQCQRCQGSLHEDVLCTSRDCPIFYMRKKVQKDLDEQDRVIQRFGPPTW

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-28Basic and acidic residues
Compositional bias39-57Acidic residues
Compositional bias58-73Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB598693
EMBL· GenBank· DDBJ
BAJ78733.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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