Essential maintenance is planned to begin on Fri Jan 24 2025. The website may be temporarily unavailable. Please use our fallback: https://wwwdev.ebi.ac.uk/uniprot/front-end/fallback/ in case of any outage.

E9QQ96 · E9QQ96_MOUSE

  • Protein
    Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
  • Gene
    Obscn
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionguanyl-nucleotide exchange factor activity
Molecular Functionhistone H2AS1 kinase activity
Biological Processphosphorylation

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF

Gene names

    • Name
      Obscn

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    E9QQ96

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Keywords

PTM databases

Expression

Gene expression databases

Structure

3D structure databases

Family & Domains

Features

Showing features for domain, region, compositional bias, coiled coil.

Type
IDPosition(s)Description
Domain9-99Ig-like
Domain109-201Ig-like
Region135-165Disordered
Compositional bias149-165Basic and acidic residues
Domain234-320Ig-like
Domain329-415Ig-like
Domain513-610Fibronectin type-III
Domain702-776Ig-like
Domain792-870Ig-like
Domain884-962Ig-like
Domain976-1054Ig-like
Domain1068-1146Ig-like
Domain1160-1238Ig-like
Domain1252-1340Ig-like
Domain1344-1422Ig-like
Domain1436-1514Ig-like
Domain1528-1606Ig-like
Domain1620-1698Ig-like
Domain1712-1790Ig-like
Domain1804-1882Ig-like
Domain1896-1984Ig-like
Domain1988-2066Ig-like
Domain2085-2174Ig-like
Domain2189-2258Ig-like
Domain2262-2348Ig-like
Domain2353-2437Ig-like
Domain2531-2614Ig-like
Domain2654-2745Ig-like
Domain2833-2917Ig-like
Domain3011-3095Ig-like
Domain3191-3275Ig-like
Domain3281-3364Ig-like
Domain3460-3543Ig-like
Domain3549-3633Ig-like
Domain3718-3809Ig-like
Domain3814-3897Ig-like
Domain3975-4058Ig-like
Domain4063-4146Ig-like
Domain4152-4234Ig-like
Domain4240-4322Ig-like
Domain4328-4410Ig-like
Domain4416-4498Ig-like
Domain4504-4586Ig-like
Domain4592-4674Ig-like
Domain4679-4762Ig-like
Domain4766-4849Ig-like
Domain4856-4940Ig-like
Domain4946-5038Ig-like
Domain5127-5216Ig-like
Domain5311-5397Ig-like
Domain5404-5498Fibronectin type-III
Domain5505-5576Ig-like
Compositional bias5633-5661Basic and acidic residues
Region5633-5669Disordered
Domain5780-5863Ig-like
Region5910-5929Disordered
Domain6010-6099Ig-like
Domain6142-6231Ig-like
Domain6253-6349Ig-like
Region6437-6479Disordered
Compositional bias6456-6472Polar residues
Domain6482-6549SH3
Domain6575-6759DH
Coiled coil6718-6745
Domain6777-6886PH
Domain6896-6979Ig-like
Domain6990-7068Ig-like
Region7121-7177Disordered
Compositional bias7126-7147Polar residues
Region7294-7322Disordered
Compositional bias7298-7315Basic and acidic residues

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    7,496
  • Mass (Da)
    815,639
  • Last updated
    2012-10-03 v2
  • MD5 Checksum
    5EA09E8EBE195F6C0F952A81761CC6CA

Computationally mapped potential isoform sequences

There are 8 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A2AAJ9OBSCN_MOUSEObscn8886
J9JIB2J9JIB2_MOUSEObscn849
Z4YJE4Z4YJE4_MOUSEObscn7176
H7BX05H7BX05_MOUSEObscn8032
A0A1W2P6H1A0A1W2P6H1_MOUSEObscn6661
F7DCJ0F7DCJ0_MOUSEObscn221
A0A571BEB2A0A571BEB2_MOUSEObscn296
F6TJX7F6TJX7_MOUSEObscn923

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias149-165Basic and acidic residues
Compositional bias5633-5661Basic and acidic residues
Compositional bias6456-6472Polar residues
Compositional bias7126-7147Polar residues
Compositional bias7298-7315Basic and acidic residues

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help