Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all alpha v integrins.Bader B.L., Rayburn H., Crowley D., Hynes R.O.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96743PubMedEurope PMCCell 95:507-519 (1998)Cited in1Mapped to63
Alpha 3 beta 1 integrin has a crucial role in kidney and lung organogenesis.Kreidberg J.A., Donovan M.J., Goldstein S.L., Rennke H., Shepherd K., Jones R.C., Jaenisch R.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96743PubMedEurope PMCDevelopment 122:3537-3547 (1996)Mapped to18
Deletion of beta 1 integrins in mice results in inner cell mass failure and peri-implantation lethality.Stephens L.E., Sutherland A.E., Klimanskaya I.V., Andrieux A., Meneses J., Pedersen R.A., Damsky C.H.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96743PubMedEurope PMCGenes Dev 9:1883-1895 (1995)Mapped to29
Adamts18 Deficiency Causes Spontaneous SMG Fibrogenesis in Adult Mice.Yang N., Zhang Q., Ye S., Lu T., Sun M., Wang L., Wang M., Pan Y.H., Dang S., Zhang W.View abstractCategoryPhenotypes & VariantsSourceMGI: 96743PubMedEurope PMCJ Dent Res 101:226-234 (2022)Mapped to99+
Extracellular matrix protein laminin beta1 regulates pain sensitivity and anxiodepression-like behaviors in mice.Li Z.Z., Han W.J., Sun Z.C., Chen Y., Sun J.Y., Cai G.H., Liu W.N., Wang T.Z., Xie Y.D.[...], Luo C.View abstractAnnotationExtracellular matrix protein laminin beta1 regulates pain sensitivity and anxiodepression-like behaviors in mice.CategoriesFunction, Phenotypes & VariantsSourceGeneRif: 16777PubMedEurope PMCJ Clin Invest 131:146323-146323 (2021)Mapped to9
A mutation affecting laminin alpha 5 polymerisation gives rise to a syndromic developmental disorder.Jones L.K., Lam R., McKee K.K., Aleksandrova M., Dowling J., Alexander S.I., Mallawaarachchi A., Cottle D.L., Short K.M.[...], Smyth I.M.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96743PubMedEurope PMCDevelopment 147:0-0 (2020)Cited in1Mapped to39
ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice.Zhu R., Pan Y.H., Sun L., Zhang T., Wang C., Ye S., Yang N., Lu T., Wisniewski T.[...], Zhang W.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96743PubMedEurope PMCNeuroscience 399:53-64 (2019)Mapped to95
A dystonia-like movement disorder with brain and spinal neuronal defects is caused by mutation of the mouse laminin beta1 subunit, Lamb1.Liu Y.B., Tewari A., Salameh J., Arystarkhova E., Hampton T.G., Brashear A., Ozelius L.J., Khodakhah K., Sweadner K.J.View abstractAnnotationA new mutant mouse (lamb1t) exhibits intermittent dystonic hindlimb movements and postures when awake and hyperextension when asleep.CategoriesSequences, Phenotypes & VariantsSourceGeneRif: 16777, MGI: 96743PubMedEurope PMCElife 4:e11102-e11102 (2015)Mapped to18
Specific activation of K-RasG12D allele in the bladder urothelium results in lung alveolar and vascular defects.Ayala de la Pena F., Kanasaki K., Kanasaki M., Vong S., Rovira C., Kalluri R.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96743PubMedEurope PMCPLoS One 9:e95888-e95888 (2014)Mapped to39
Mutations in LAMB1 cause cobblestone brain malformation without muscular or ocular abnormalities.Radmanesh F., Caglayan A.O., Silhavy J.L., Yilmaz C., Cantagrel V., Omar T., Rosti B., Kaymakcalan H., Gabriel S.[...], Gleeson J.G.View abstractCategoriesSequences, Phenotypes & VariantsSourceMGI: 96743PubMedEurope PMCAm. J. Hum. Genet. 92:468-474 (2013)Cited in2Mapped to63
A conditional knockout resource for the genome-wide study of mouse gene function.Skarnes W.C., Rosen B., West A.P., Koutsourakis M., Bushell W., Iyer V., Mujica A.O., Thomas M., Harrow J.[...], Bradley A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96743PubMedEurope PMCNature 474:337-342 (2011)Mapped to99+
A high-resolution anatomical ontology of the developing murine genitourinary tract.Little M.H., Brennan J., Georgas K., Davies J.A., Davidson D.R., Baldock R.A., Beverdam A., Bertram J.F., Capel B.[...], Yu J.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96743PubMedEurope PMCGene Expr Patterns 7:680-699 (2007)Mapped to87
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.Zambrowicz B.P., Abuin A., Ramirez-Solis R., Richter L.J., Piggott J., BeltrandelRio H., Buxton E.C., Edwards J., Finch R.A.[...], Sands A.T.View abstractCategoryPhenotypes & VariantsSourceMGI: 96743PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 100:14109-14114 (2003)Cited in1Mapped to99+
Anuria, omphalocele, and perinatal lethality in mice lacking the CD34- related protein podocalyxin.Doyonnas R., Kershaw D.B., Duhme C., Merkens H., Chelliah S., Graf T., McNagny K.M.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96743PubMedEurope PMCJ. Exp. Med. 194:13-27 (2001)Cited in1Mapped to67
Gelatinase B (MMP-9) is not essential in the normal kidney and does not influence progression of renal disease in a mouse model of Alport syndrome.Andrews K.L., Betsuyaku T., Rogers S., Shipley J.M., Senior R.M., Miner J.H.View abstractCategoriesSequences, Phenotypes & VariantsSourceMGI: 96743PubMedEurope PMCAm J Pathol 157:303-311 (2000)Mapped to37