E9QH31 · E9QH31_DANRE
- ProteinAldehyde dehydrogenase
- Genealdh3a2b
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids490 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
Catalytic activity
- (2E)-hexadecenal + H2O + NAD+ = (E)-hexadec-2-enoate + 2 H+ + NADH
- 2 H+ + hexadecanoate + NADH = H2O + hexadecanal + NAD+
- 2,6,10,14-tetramethylpentadecanal + H2O + NAD+ = 2,6,10,14-tetramethylpentadecanoate + 2 H+ + NADH
- 22-oxodocosanoate + H2O + NAD+ = docosanedioate + 2 H+ + NADH
- H2O + NAD+ + octadecanal = 2 H+ + NADH + octadecanoate
- H2O + NAD+ + octanal = 2 H+ + NADH + octanoate
- H2O + NAD+ + tetradecanal = 2 H+ + NADH + tetradecanoate
- H2O + heptanal + NAD+ = 2 H+ + heptanoate + NADH
- a fatty aldehyde + H2O + NAD+ = a fatty acid + 2 H+ + NADH
- decanal + H2O + NAD+ = decanoate + 2 H+ + NADH
- dodecanoate + 2 H+ + NADH = dodecanal + H2O + NAD+
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 210 | |||||
Sequence: E | ||||||
Active site | 244 | |||||
Sequence: C |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | endoplasmic reticulum membrane | |
Molecular Function | 3-chloroallyl aldehyde dehydrogenase activity | |
Molecular Function | aldehyde dehydrogenase (NAD+) activity | |
Biological Process | cellular aldehyde metabolic process | |
Biological Process | fatty acid metabolic process |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameAldehyde dehydrogenase
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionE9QH31
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Endoplasmic reticulum membrane ; Single-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 470-488 | Helical | ||||
Sequence: MAMLALMVVFAAVIIQKYF |
Keywords
- Cellular component
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 5-426 | Aldehyde dehydrogenase | ||||
Sequence: QKAVERARKAFFTGRSKSLEYRISQLKNLQRFMQERQKEIAEALKKDLKRSEFGTSLYETLGVESEINLALKKLKEWAAPRPVNKSLMTISDQVYIQPEPLGVVLIIGAWNYPWAVTVGPLVGAIAAGNAAVIKPSEVSAHTSKVMEEFLPLYLDKELYPVVTGGVKETQELLKQRFDHIFYTGNGMVGKIIMEAAAKHLTPTTLELGGKSPCYIDKDCDLTIACRRIAWGKYSNCGQTCIAPDYILCDPSIQDRVIEEIKKNIKEFYTENPQKCPDYGRIINQRHFKRLMSLMEGSSIAVSGEHNEAECYIAPTVLRDVKPDAKVMQEEIFGPLLPIVTVNSVDEAIKFINQRDKPLALYIFSSDKKLIDRMIAETSSGGLMANDCLMHFSVSSLPFGGVGDSGMGRYHGKHGFDNLSHMR |
Sequence similarities
Belongs to the aldehyde dehydrogenase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length490
- Mass (Da)55,060
- Last updated2011-09-21 v2
- Checksum081558B1890338EF
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CU463284 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |