E9QE31 · E9QE31_DANRE

Function

function

Calcium-regulated non-lysosomal thiol-protease.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Features

Showing features for active site.

1723100200300400500600700
TypeIDPosition(s)Description
Active site120
Active site277

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleolus
Molecular Functioncalcium ion binding
Molecular Functioncalcium-dependent cysteine-type endopeptidase activity
Molecular Functionpeptidase activity
Biological Processcalcium-dependent self proteolysis
Biological Processnegative regulation of apoptotic process
Biological Processprotein catabolic process
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Calpain-3
  • EC number

Gene names

    • Name
      capn3b
    • Synonyms
      si:dkey-12h9.9

Organism names

  • Taxonomic identifier
  • Strain
    • Tuebingen
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    E9QE31
  • Secondary accessions
    • A0A8M1P227

Proteomes

    • Identifier
    • Component
      Alternate scaffold 20, Chromosome 20

Organism-specific databases

Subcellular Location

Keywords

Expression

Gene expression databases

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain65-360Calpain catalytic
Domain624-659EF-hand
Domain689-723EF-hand

Sequence similarities

Belongs to the peptidase C2 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    723
  • Mass (Da)
    83,174
  • Last updated
    2016-01-20 v2
  • Checksum
    2EEC5DEE1CB803C9
MAEEQKFSETSVQLTEAAPQTVGSGFTAPGNIYSAILSRNEAVKDARRLKDFQELRDKYVRKKVLFEDPLFPAQDSSLFYSEKFPLKLEWKRPMEICKNPQFILGGANRTDICQGDLGDCWLLAAIACLTLNDVILKRVVPHDQSFTENYAGIFHFQFWRYGEWVDVVIDDRLPTYKNKLVFTRSGQNNEFWSALMEKAYAKLHGSYEALKGGNSLEAMEDFTGGVTEFYEITEAPKELYNIMRKALKRGSLMGCAIDTLVPTAQRTKTASGLVRGHAYSVTGVEQGKRKDGKDLMIRLVRVRDPWGVAPPPACKSNDWVELAKTEQDKQRLQPGEQGEFWMCFEEFQKNFTKLEICNLTPDTLEDDQMFKWNVTVHEGRWVKGCSAGGCRNFPDTYWTNPQFRLVLLEADAKEKTCTVVVALMQKGRRVERCSGATLHNIGFAIYEVPKEMKGNQQQQLSKDFFLYNASTARSKSYVNIREVTERFCLKPGEYVIIPSTFDPHKESEFLLRVFSENRSTSKVIDAEIEAEPMQVDNVKKKIKPFEEEETEEEKQFRAIFQQIAGDDMEINANELRTVLNRVVAKHKELKTEGFSLESCRSMIALLDTDGTGHLNLQEFKHLWNKIKQWKLVFTRFDTDKSSTISSFEMRNALTEAGFQLNNQLYDIICMRYANEHMELDFDSYISCLVRLEGMFRAFRAFDKDGDGLIKLNVFEWLQLTMYA

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8M9PSG7A0A8M9PSG7_DANREcapn3b722

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AL954831
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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