E9Q9Y2 · E9Q9Y2_MOUSE
- ProteinNuclear receptor corepressor 1
- GeneNcor1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1399 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score1/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Biological Process | negative regulation of DNA-templated transcription |
Names & Taxonomy
Protein names
- Recommended nameNuclear receptor corepressor 1
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineagecellular organisms > Eukaryota (eucaryotes) > Opisthokonta > Metazoa (metazoans) > Eumetazoa > Bilateria > Deuterostomia > Chordata (chordates) > Craniata > Vertebrata (vertebrates) > Gnathostomata (jawed vertebrates) > Teleostomi > Euteleostomi (bony vertebrates) > Sarcopterygii > Dipnotetrapodomorpha > Tetrapoda (tetrapods) > Amniota (amniotes) > Mammalia (mammals) > Theria > Eutheria (placentals) > Boreoeutheria > Euarchontoglires > Glires (Rodents and rabbits) > Rodentia (rodent) > Myomorpha (mice and others) > Muroidea > Muridae > Murinae > Mus (mice) > Mus
Accessions
- Primary accessionE9Q9Y2
Proteomes
Organism-specific databases
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-68 | Disordered | ||||
Sequence: MSAARYSVPPVLQPAPHQVITNLPEGVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMGGSISQGTPG | ||||||
Compositional bias | 45-68 | Polar residues | ||||
Sequence: SKTTVASEKPSFIMGGSISQGTPG | ||||||
Region | 396-493 | Disordered | ||||
Sequence: GEPVRARHTSVVSSGPSVLRSTLHEAPKAQLSPGLYDDSSARRTPVSYQNTISRGSPMMNRTSDVSSSKSASHERKSTLTPTQRESIPAKSPVPGVDP | ||||||
Compositional bias | 437-482 | Polar residues | ||||
Sequence: RRTPVSYQNTISRGSPMMNRTSDVSSSKSASHERKSTLTPTQRESI | ||||||
Region | 644-726 | Disordered | ||||
Sequence: RPYNAASLSPGHPTHLAAAASAEREREREREKERERERERERERERERIAAAPADLYLRPGSEQPGRPGSHGYVRSPSPSVRT | ||||||
Compositional bias | 662-695 | Basic and acidic residues | ||||
Sequence: AASAEREREREREKERERERERERERERERIAAA | ||||||
Region | 849-887 | Disordered | ||||
Sequence: ALPSGKAQPHASVVYSEAGKDKGPPPKSRYEEELRTRGK | ||||||
Compositional bias | 870-886 | Basic and acidic residues | ||||
Sequence: KGPPPKSRYEEELRTRG | ||||||
Region | 906-1006 | Disordered | ||||
Sequence: SDKDARERGSQSSDSSSSLSSHRYETASDAIEVISPASSPAPPQEKPQAYQPDMVKANQAENESTRQYEGPLHHYRSQQESPSPQQQPPLPPSSQSEGMGQ | ||||||
Compositional bias | 916-930 | Polar residues | ||||
Sequence: QSSDSSSSLSSHRYE | ||||||
Compositional bias | 960-988 | Polar residues | ||||
Sequence: VKANQAENESTRQYEGPLHHYRSQQESPS | ||||||
Compositional bias | 1032-1074 | Polar residues | ||||
Sequence: QVPSQPSTSTFQTSPSALSSTPVRTKTSSRYSPESQSQTVLHP | ||||||
Region | 1032-1120 | Disordered | ||||
Sequence: QVPSQPSTSTFQTSPSALSSTPVRTKTSSRYSPESQSQTVLHPRPGPRVSPENLVDKSRGRPGKSPERSHIPSEPYEPISPPQGPAVHE | ||||||
Compositional bias | 1085-1102 | Basic and acidic residues | ||||
Sequence: LVDKSRGRPGKSPERSHI | ||||||
Region | 1249-1342 | Disordered | ||||
Sequence: PVGIMPGSASTSVVTSSEARRDEGEPSPHAGVCKPKLINKSNSRKSKSPIPGQSYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQF | ||||||
Compositional bias | 1290-1320 | Polar residues | ||||
Sequence: NSRKSKSPIPGQSYLGTERPSSVSSVHSEGD | ||||||
Region | 1372-1399 | Disordered | ||||
Sequence: PHQQNRIWEREPAPLLSAQYETLSDSDD |
Sequence similarities
Belongs to the N-CoR nuclear receptor corepressors family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,399
- Mass (Da)151,490
- Last updated2011-04-05 v1
- Checksum0C1349D573CFFFDF
Computationally mapped potential isoform sequences
There are 14 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q60974 | NCOR1_MOUSE | Ncor1 | 2453 | ||
F7C134 | F7C134_MOUSE | Ncor1 | 1389 | ||
E9Q8K6 | E9Q8K6_MOUSE | Ncor1 | 791 | ||
Q8BK32 | Q8BK32_MOUSE | Ncor1 | 291 | ||
Q5RIM6 | Q5RIM6_MOUSE | Ncor1 | 2454 | ||
Q5RIN0 | Q5RIN0_MOUSE | Ncor1 | 541 | ||
E9Q2B2 | E9Q2B2_MOUSE | Ncor1 | 2386 | ||
F6SFD2 | F6SFD2_MOUSE | Ncor1 | 261 | ||
Q3UV08 | Q3UV08_MOUSE | Ncor1 | 993 | ||
Q8CHB6 | Q8CHB6_MOUSE | Ncor1 | 1724 | ||
F6TWR1 | F6TWR1_MOUSE | Ncor1 | 254 | ||
E0CYX5 | E0CYX5_MOUSE | Ncor1 | 163 | ||
F6U338 | F6U338_MOUSE | Ncor1 | 216 | ||
F6TRR6 | F6TRR6_MOUSE | Ncor1 | 157 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 45-68 | Polar residues | ||||
Sequence: SKTTVASEKPSFIMGGSISQGTPG | ||||||
Compositional bias | 437-482 | Polar residues | ||||
Sequence: RRTPVSYQNTISRGSPMMNRTSDVSSSKSASHERKSTLTPTQRESI | ||||||
Compositional bias | 662-695 | Basic and acidic residues | ||||
Sequence: AASAEREREREREKERERERERERERERERIAAA | ||||||
Compositional bias | 870-886 | Basic and acidic residues | ||||
Sequence: KGPPPKSRYEEELRTRG | ||||||
Compositional bias | 916-930 | Polar residues | ||||
Sequence: QSSDSSSSLSSHRYE | ||||||
Compositional bias | 960-988 | Polar residues | ||||
Sequence: VKANQAENESTRQYEGPLHHYRSQQESPS | ||||||
Compositional bias | 1032-1074 | Polar residues | ||||
Sequence: QVPSQPSTSTFQTSPSALSSTPVRTKTSSRYSPESQSQTVLHP | ||||||
Compositional bias | 1085-1102 | Basic and acidic residues | ||||
Sequence: LVDKSRGRPGKSPERSHI | ||||||
Compositional bias | 1290-1320 | Polar residues | ||||
Sequence: NSRKSKSPIPGQSYLGTERPSSVSSVHSEGD |
Keywords
- Technical term