Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L.[...], Ponting C.P.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol. 7:E1000112-E1000112 (2009)Cited in99+99+
Modernizing reference genome assemblies.Church D.M., Schneider V.A., Graves T., Auger K., Cunningham F., Bouk N., Chen H.C., Agarwala R., McLaren W.M.[...], Hubbard T.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol 9:e1001091-e1001091 (2011)Cited in99+
No title available.EnsemblCited forIDENTIFICATIONStrainC57BL/6JSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to UniProtKB (AUG-2024)Cited in99+
Genetic determinants of micronucleus formation in vivo.Adams D.J., Barlas B., McIntyre R.E., Salguero I., van der Weyden L., Barros A., Vicente J.R., Karimpour N., Haider A.[...], White J.K.View abstractSourceMGI: 1923038PubMedEurope PMCNature 627:130-136 (2024)Mapped to99+
Smurf1 Modulates Smad Signaling Pathway in Fibrotic Cataract Formation.Jiang F., Yang Y., Ni Y., Qin Y., Yuan F., Ju R., Wu M.View abstractAnnotationSmurf1 Modulates Smad Signaling Pathway in Fibrotic Cataract Formation.SourceGeneRif: 75788PubMedEurope PMCInvest Ophthalmol Vis Sci 65:18-18 (2024)Mapped to5
SMURF1 activates the cGAS/STING/IFN-1 signal axis by mediating YY1 ubiquitination to accelerate the progression of lupus nephritis.Li X., Tao S., Xu Z., Ren Y., Xiang W., He X.View abstractAnnotationSMURF1 activates the cGAS/STING/IFN-1 signal axis by mediating YY1 ubiquitination to accelerate the progression of lupus nephritis.SourceGeneRif: 75788PubMedEurope PMCAutoimmunity 56:2281235-2281235 (2023)Mapped to11
piR-368 promotes odontoblastic differentiation of dental papilla cells via the Smad1/5 signaling pathway by targeting Smurf1.Xing X., She Y., Yuan G., Yang G.View abstractAnnotationpiR-368 promotes odontoblastic differentiation of dental papilla cells via the Smad1/5 signaling pathway by targeting Smurf1.CategoryPhenotypes & VariantsSourceGeneRif: 75788PubMedEurope PMCConnect Tissue Res 65:53-62 (2024)Mapped to5
Talin-1 inhibits Smurf1-mediated Stat3 degradation to modulate beta-cell proliferation and mass in mice.Hou X., Chen Y., Zhou B., Tang W., Ding Z., Chen L., Wu Y., Yang H., Du C.[...], Cao H.View abstractAnnotationTalin-1 inhibits Smurf1-mediated Stat3 degradation to modulate beta-cell proliferation and mass in mice.CategoryFunctionSourceGeneRif: 75788, MGI: 1923038PubMedEurope PMCCell Death Dis 14:709-709 (2023)Mapped to23
The degradation of TGR5 mediated by Smurf1 contributes to diabetic nephropathy.Lin Z., Li S., Xiao H., Xu Z., Li C., Zeng J., Wang S., Liu Z., Huang H.View abstractAnnotationThe degradation of TGR5 mediated by Smurf1 contributes to diabetic nephropathy.CategorySubcellular LocationSourceGeneRif: 75788, MGI: 1923038PubMedEurope PMCCell Rep 42:112851-112851 (2023)Mapped to8
A Golgi-resident GPR108 cooperates with E3 ubiquitin ligase Smurf1 to suppress antiviral innate immunity.Zhao M., Zhang Y., Qiang L., Lu Z., Zhao Z., Fu Y., Wu B., Chai Q., Ge P.[...], Liu C.H.View abstractAnnotationA Golgi-resident GPR108 cooperates with E3 ubiquitin ligase Smurf1 to suppress antiviral innate immunity.CategoryFunctionSourceGeneRif: 75788, MGI: 1923038PubMedEurope PMCCell Rep 42:112655-112655 (2023)Mapped to15
Smurf1 regulates ameloblast polarization by ubiquitination-mediated degradation of RhoA.Niu H., Bi F., Zhao W., Xu Y., Han Q., Guo W., Chen Y.View abstractAnnotationSmurf1 regulates ameloblast polarization by ubiquitination-mediated degradation of RhoA.CategoriesFunction, ExpressionSourceGeneRif: 75788PubMedEurope PMCCell Prolif 56:e13387-e13387 (2023)Mapped to5
HSP90beta chaperoning SMURF1-mediated LATS proteasomal degradation in the regulation of bone formation.Qu M., Gong Y., Jin Y., Gao R., He Q., Xu Y., Shen T., Mei L., Xu C.[...], Wu X.View abstractAnnotationHSP90beta chaperoning SMURF1-mediated LATS proteasomal degradation in the regulation of bone formation.CategoriesFunction, InteractionSourceGeneRif: 75788PubMedEurope PMCCell Signal 102:110523-110523 (2023)Mapped to6
Deletion of Smurf1 attenuates liver steatosis via stabilization of p53.Lin W., Zhang X., Zhang C., Li L., Zhang J., Xie P., Zhan Y., An W.View abstractAnnotationDeletion of Smurf1 attenuates liver steatosis via stabilization of p53.CategoryFunctionSourceGeneRif: 75788PubMedEurope PMCLab Invest 102:1075-1087 (2022)Mapped to26
Overexpression of miR-195-5p reduces osteoporosis through activating BMP- 2/SMAD/Akt/RUNX2 pathway via targeting SMURF1.Ye L.C., Qian L.F., Liang L., Jiang L.J., Che Z.Y., Guo Y.H.View abstractAnnotationOverexpression of miR-195-5p reduces osteoporosis through activating BMP-2/SMAD/Akt/RUNX2 pathway via targeting SMURF1.CategoryFunctionSourceGeneRif: 75788PubMedEurope PMCJ Biol Regul Homeost Agents 35:0-0 (2021)Mapped to5
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.Bedogni F., Hevner R.F.View abstractSourceMGI: 1923038PubMedEurope PMCFront Mol Neurosci 14:686034-686034 (2021)Mapped to99+
MicroRNA 379 Regulates Klotho Deficiency-Induced Cardiomyocyte Apoptosis Via Repression of Smurf1.Chen K., Zhang B., Sun Z.View abstractAnnotationMicroRNA 379 Regulates Klotho Deficiency-Induced Cardiomyocyte Apoptosis Via Repression of Smurf1.CategoriesFunction, ExpressionSourceGeneRif: 75788PubMedEurope PMCHypertension 78:342-352 (2021)Mapped to5
Smurf1 aggravates non-alcoholic fatty liver disease by stabilizing SREBP- 1c in an E3 activity-independent manner.Zhang X., Zhan Y., Lin W., Zhao F., Guo C., Chen Y., Du M., Li D., Zhang L.[...], Xie P.View abstractAnnotationSmurf1 aggravates non-alcoholic fatty liver disease by stabilizing SREBP-1c in an E3 activity-independent manner.CategoryInteractionSourceGeneRif: 75788PubMedEurope PMCFASEB J 34:7631-7643 (2020)Mapped to7
Non-proteolytic ubiquitin modification of PPARgamma by Smurf1 protects the liver from steatosis.Zhu K., Tang Y., Xu X., Dang H., Tang L.Y., Wang X., Wang X.W., Zhang Y.E.View abstractCategoryFunctionSourceMGI: 1923038PubMedEurope PMCPLoS Biol 16:e3000091-e3000091 (2018)Mapped to22
CRTC2 suppresses BMP2-induced osteoblastic differentiation via Smurf1 expression in MC3T3-E1 cells.Kim K.M., Jeon W.J., Kim E.J., Jang W.G.View abstractAnnotationSmurf1 expression in osteoblast differentiation is regulated by CRTC2.CategoriesFunction, InteractionSourceGeneRif: 75788PubMedEurope PMCLife Sci 214:70-76 (2018)Mapped to9
VCP/p97 increases BMP signaling by accelerating ubiquitin ligase Smurf1 degradation.Li H., Cui Y., Wei J., Liu C., Chen Y., Cui C.P., Li L., Zhang X., Zhang L.View abstractCategoriesPTM / Processing, InteractionSourceMGI: 1923038PubMedEurope PMCFASEB J 33:2928-2943 (2019)Mapped to8
Inhibition of osteoblastic Smurf1 promotes bone formation in mouse models of distinctive age-related osteoporosis.Liang C., Peng S., Li J., Lu J., Guan D., Jiang F., Lu C., Li F., He X.[...], Zhang G.View abstractAnnotationInhibition of osteoblastic Smurf1 promotes bone formation in mouse models of distinctive age-related osteoporosisCategoriesFunction, InteractionSourceGeneRif: 75788, MGI: 1923038PubMedEurope PMCNat Commun 9:3428-3428 (2018)Mapped to6
The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development.Koefoed K., Skat-Rordam J., Andersen P., Warzecha C.B., Pye M., Andersen T.A., Ajbro K.D., Bendsen E., Narimatsu M.[...], Larsen L.A.View abstractAnnotationSMURF1 is a critical regulator of outflow tract septation and cell-type specification during heart developmentCategoriesFunction, InteractionSourceGeneRif: 75788, MGI: 1923038PubMedEurope PMCSci Rep 8:9542-9542 (2018)Mapped to21
Bmp2 and Notch cooperate to pattern the embryonic endocardium.Papoutsi T., Luna-Zurita L., Prados B., Zaffran S., de la Pompa J.L.View abstractCategoriesFunction, InteractionSourceMGI: 1923038PubMedEurope PMCDevelopment 145:dev163378-dev163378 (2018)Mapped to99+
Smad ubiquitylation regulatory factor 1 promotes LIM-homeobox gene 9 degradation and represses testosterone production in Leydig cells.Hu F., Zhu Q., Sun B., Cui C., Li C., Zhang L.View abstractAnnotationthat Smurf1 promotes Lhx9 ubiquitylation and is involved in testosterone production in Leydig cells directlyCategoriesFunction, InteractionSourceGeneRif: 75788, MGI: 1923038PubMedEurope PMCFASEB J 32:4627-4640 (2018)Mapped to13
Smurf1 regulates macrophage proliferation, apoptosis and migration via JNK and p38 MAPK signaling pathways.Guo J., Qiu X., Zhang L., Wei R.View abstractAnnotationSmurf1 is a new positive regulator for macrophage proliferation and apoptosis but a negative regulator for macrophage migration.CategoriesFunction, PTM / Processing, InteractionSourceGeneRif: 75788PubMedEurope PMCMol Immunol 97:20-26 (2018)Mapped to5