E9Q4H1 · E9Q4H1_MOUSE
- ProteinAPC, WNT signaling pathway regulator
- GeneApc
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1133 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cell periphery | |
Cellular Component | intracellular membrane-bounded organelle | |
Molecular Function | beta-catenin binding | |
Biological Process | negative regulation of Wnt signaling pathway | |
Biological Process | Wnt signaling pathway |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionE9Q4H1
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, coiled coil, compositional bias, repeat.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 16-47 | Disordered | ||||
Sequence: SVPPVTLGARSSGGGRGRVPGEGRRPGGARAC | ||||||
Coiled coil | 142-176 | |||||
Sequence: LEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKR | ||||||
Compositional bias | 216-243 | Basic and acidic residues | ||||
Sequence: QDMEKRAQRSSQSRHDAASHEAGRQHEG | ||||||
Region | 216-286 | Disordered | ||||
Sequence: QDMEKRAQRSSQSRHDAASHEAGRQHEGHGVAESNTAASSSGQSPATRVDHETASVLSSSGTHSAPRRLTS | ||||||
Compositional bias | 247-284 | Polar residues | ||||
Sequence: AESNTAASSSGQSPATRVDHETASVLSSSGTHSAPRRL | ||||||
Repeat | 640-682 | ARM | ||||
Sequence: NCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMG | ||||||
Region | 810-855 | Disordered | ||||
Sequence: VLPSSSSSRGSLDSSRSEKDRSLERERGIGLSAYHPTTENAGTSSK | ||||||
Compositional bias | 822-837 | Basic and acidic residues | ||||
Sequence: DSSRSEKDRSLERERG | ||||||
Region | 903-924 | Disordered | ||||
Sequence: RRSSASHTHSNTYNFTKSENSN | ||||||
Compositional bias | 906-924 | Polar residues | ||||
Sequence: SASHTHSNTYNFTKSENSN | ||||||
Compositional bias | 938-955 | Polar residues | ||||
Sequence: RSSNDSLNSVTSSDGYGK | ||||||
Region | 938-968 | Disordered | ||||
Sequence: RSSNDSLNSVTSSDGYGKRGQMKPSVESYSE | ||||||
Region | 1040-1061 | Disordered | ||||
Sequence: IKQNEQRQARSQNTSYPVYSEN | ||||||
Compositional bias | 1046-1060 | Polar residues | ||||
Sequence: RQARSQNTSYPVYSE | ||||||
Region | 1074-1133 | Disordered | ||||
Sequence: GQQECVSPYRSRGTSGSETNRMGSSHAINQNVNQSLCQEDDYEDDKPTNYSERYSEEEQH | ||||||
Compositional bias | 1080-1110 | Polar residues | ||||
Sequence: SPYRSRGTSGSETNRMGSSHAINQNVNQSLC | ||||||
Compositional bias | 1112-1133 | Basic and acidic residues | ||||
Sequence: EDDYEDDKPTNYSERYSEEEQH |
Sequence similarities
Belongs to the adenomatous polyposis coli (APC) family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusFragment
- Length1,133
- Mass (Da)125,746
- Last updated2011-04-05 v1
- Checksum98CB3BC94E75DA29
Computationally mapped potential isoform sequences
There are 6 potential isoforms mapped to this entry
Features
Showing features for compositional bias, non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 216-243 | Basic and acidic residues | ||||
Sequence: QDMEKRAQRSSQSRHDAASHEAGRQHEG | ||||||
Compositional bias | 247-284 | Polar residues | ||||
Sequence: AESNTAASSSGQSPATRVDHETASVLSSSGTHSAPRRL | ||||||
Compositional bias | 822-837 | Basic and acidic residues | ||||
Sequence: DSSRSEKDRSLERERG | ||||||
Compositional bias | 906-924 | Polar residues | ||||
Sequence: SASHTHSNTYNFTKSENSN | ||||||
Compositional bias | 938-955 | Polar residues | ||||
Sequence: RSSNDSLNSVTSSDGYGK | ||||||
Compositional bias | 1046-1060 | Polar residues | ||||
Sequence: RQARSQNTSYPVYSE | ||||||
Compositional bias | 1080-1110 | Polar residues | ||||
Sequence: SPYRSRGTSGSETNRMGSSHAINQNVNQSLC | ||||||
Compositional bias | 1112-1133 | Basic and acidic residues | ||||
Sequence: EDDYEDDKPTNYSERYSEEEQH | ||||||
Non-terminal residue | 1133 | |||||
Sequence: H |
Keywords
- Technical term