CREB proteins function as positive regulators of the translocated bcl-2 allele in t(14;18) lymphomas.Ji L., Mochon E., Arcinas M., Boxer L.M.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1298366PubMedEurope PMCJ Biol Chem 271:22687-22691 (1996)Mapped to37
Overexpression of activation transcriptional factor 1 in lymphomas and in activated lymphocytes.Hsueh Y.P., Lai M.Z.View abstractCategoryFunctionSourceMGI: 1298366PubMedEurope PMCJ Immunol 154:5675-5683 (1995)Mapped to10
Hematoma Resolution In Vivo Is Directed by Activating Transcription Factor 1.Seneviratne A., Han Y., Wong E., Walter E.R.H., Jiang L., Cave L., Long N.J., Carling D., Mason J.C.[...], Boyle J.J.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1298366PubMedEurope PMCCirc Res 127:928-944 (2020)Mapped to16
Colorectal Cancer-Associated Genes Are Associated with Tooth Agenesis and May Have a Role in Tooth Development.Williams M.A., Biguetti C., Romero-Bustillos M., Maheshwari K., Dinckan N., Cavalla F., Liu X., Silva R., Akyalcin S.[...], Letra A.View abstractCategoryFunctionSourceMGI: 1298366PubMedEurope PMCSci Rep 8:2979-2979 (2018)Mapped to12
The transcription factor Mesp1 interacts with cAMP-responsive element binding protein 1 (Creb1) and coactivates Ets variant 2 (Etv2) gene expression.Shi X., Zirbes K.M., Rasmussen T.L., Ferdous A., Garry M.G., Koyano-Nakagawa N., Garry D.J.View abstractCategoriesFunction, InteractionSourceMGI: 1298366PubMedEurope PMCJ Biol Chem 290:9614-9625 (2015)Mapped to84
Adenosine derived from ecto-nucleotidases in calcific aortic valve disease promotes mineralization through A2a adenosine receptor.Mahmut A., Boulanger M.C., Bouchareb R., Hadji F., Mathieu P.View abstractCategoriesFunction, ExpressionSourceMGI: 1298366PubMedEurope PMCCardiovasc Res 106:109-120 (2015)Mapped to58
ATF1 modulates the heat shock response by regulating the stress-inducible heat shock factor 1 transcription complex.Takii R., Fujimoto M., Tan K., Takaki E., Hayashida N., Nakato R., Shirahige K., Nakai A.View abstractCategoryFunctionSourceMGI: 1298366PubMedEurope PMCMol Cell Biol 35:11-25 (2015)Mapped to24
EWS/ATF1 expression induces sarcomas from neural crest-derived cells in mice.Yamada K., Ohno T., Aoki H., Semi K., Watanabe A., Moritake H., Shiozawa S., Kunisada T., Kobayashi Y.[...], Yamada Y.View abstractCategoriesFunction, ExpressionSourceMGI: 1298366PubMedEurope PMCJ Clin Invest 123:600-610 (2013)Mapped to25
PGE(2) induces macrophage IL-10 production and a regulatory-like phenotype via a protein kinase A-SIK-CRTC3 pathway.MacKenzie K.F., Clark K., Naqvi S., McGuire V.A., Noehren G., Kristariyanto Y., van den Bosch M., Mudaliar M., McCarthy P.C.[...], Arthur J.S.View abstractCategoryFunctionSourceMGI: 1298366PubMedEurope PMCJ Immunol 190:565-577 (2013)Mapped to34
MicroRNA-34c enhances murine male germ cell apoptosis through targeting ATF1.Liang X., Zhou D., Wei C., Luo H., Liu J., Fu R., Cui S.View abstractCategoryFunctionSourceMGI: 1298366PubMedEurope PMCPLoS One 7:e33861-e33861 (2012)Mapped to10
A conditional knockout resource for the genome-wide study of mouse gene function.Skarnes W.C., Rosen B., West A.P., Koutsourakis M., Bushell W., Iyer V., Mujica A.O., Thomas M., Harrow J.[...], Bradley A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1298366PubMedEurope PMCNature 474:337-342 (2011)Mapped to99+
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.Yokoyama S., Ito Y., Ueno-Kudoh H., Shimizu H., Uchibe K., Albini S., Mitsuoka K., Miyaki S., Kiso M.[...], Asahara H.View abstractCategoryFunctionSourceMGI: 1298366PubMedEurope PMCDev. Cell 17:836-848 (2009)Cited in1Mapped to99+
The presence and activation of two essential transcription factors (cAMP response element-binding protein and cAMP-dependent transcription factor ATF1) in the two-cell mouse embryo.Jin X.L., O'Neill C.View abstractCategoriesFunction, PTM / ProcessingSourceMGI: 1298366PubMedEurope PMCBiol Reprod 82:459-468 (2010)Mapped to77
ATF-1 is a hypoxia-responsive transcriptional activator of skeletal muscle mitochondrial-uncoupling protein 3.Lu Z., Sack M.N.View abstractCategoryFunctionSourceMGI: 1298366PubMedEurope PMCJ Biol Chem 283:23410-23418 (2008)Mapped to20
EUCOMM--the European conditional mouse mutagenesis program.Friedel R.H., Seisenberger C., Kaloff C., Wurst W.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1298366PubMedEurope PMCBrief Funct Genomic Proteomic 6:180-185 (2007)Mapped to99+
Specific ablation of the transcription factor CREB in sympathetic neurons surprisingly protects against developmentally regulated apoptosis.Parlato R., Otto C., Begus Y., Stotz S., Schutz G.View abstractCategoryFunctionSourceMGI: 1298366PubMedEurope PMCDevelopment 134:1663-1670 (2007)Mapped to67
Hypothalamic 3',5'-cyclic adenosine monophosphate response element-binding protein loss causes anterior pituitary hypoplasia and dwarfism in mice.Mantamadiotis T., Kretz O., Ridder S., Bleckmann S.C., Bock D., Grone H.J., Malaterre J., Dworkin S., Ramsay R.G., Schutz G.View abstractCategoryFunctionSourceMGI: 1298366PubMedEurope PMCMol Endocrinol 20:204-211 (2006)Mapped to78
Protein kinase A signalling via CREB controls myogenesis induced by Wnt proteins.Chen A.E., Ginty D.D., Fan C.M.View abstractCategoryFunctionSourceMGI: 1298366PubMedEurope PMCNature 433:317-322 (2005)Mapped to72
CREB function is required for normal thymic cellularity and post- irradiation recovery.Baumann S., Kyewski B., Bleckmann S.C., Greiner E., Rudolph D., Schmid W., Ramsay R.G., Krammer P.H., Schutz G., Mantamadiotis T.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1298366PubMedEurope PMCEur J Immunol 34:1961-1971 (2004)Mapped to21
Induction of Grp78/BiP by translational block: activation of the Grp78 promoter by ATF4 through and upstream ATF/CRE site independent of the endoplasmic reticulum stress elements.Luo S., Baumeister P., Yang S., Abcouwer S.F., Lee A.S.View abstractCategoryFunctionSourceMGI: 1298366PubMedEurope PMCJ Biol Chem 278:37375-37385 (2003)Mapped to36
Modulation of CREB activity by the Rho GTPase regulates cell and organism size during mouse embryonic development.Sordella R., Classon M., Hu K.Q., Matheson S.F., Brouns M.R., Fine B., Zhang L., Takami H., Yamada Y., Settleman J.View abstractCategoryFunctionSourceMGI: 1298366PubMedEurope PMCDev Cell 2:553-565 (2002)Mapped to57
Reversible inhibition of CREB/ATF transcription factors in region CA1 of the dorsal hippocampus disrupts hippocampus-dependent spatial memory.Pittenger C., Huang Y.Y., Paletzki R.F., Bourtchouladze R., Scanlin H., Vronskaya S., Kandel E.R.View abstractCategoryFunctionSourceMGI: 1298366PubMedEurope PMCNeuron 34:447-462 (2002)Mapped to21
Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB.Lonze B.E., Riccio A., Cohen S., Ginty D.D.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1298366PubMedEurope PMCNeuron 34:371-385 (2002)Mapped to90
Disruption of CREB function in brain leads to neurodegeneration.Mantamadiotis T., Lemberger T., Bleckmann S.C., Kern H., Kretz O., Martin Villalba A., Tronche F., Kellendonk C., Gau D.[...], Schutz G.View abstractCategoryFunctionSourceMGI: 1298366PubMedEurope PMCNat Genet 31:47-54 (2002)Mapped to58
MSK1 and MSK2 are required for the mitogen- and stress-induced phosphorylation of CREB and ATF1 in fibroblasts.Wiggin G.R., Soloaga A., Foster J.M., Murray-Tait V., Cohen P., Arthur J.S.View abstractCategoryFunctionSourceMGI: 1298366PubMedEurope PMCMol. Cell. Biol. 22:2871-2881 (2002)Cited in5Mapped to14