E9PUJ2 · E9PUJ2_MOUSE
- ProteinRAD50 double strand break repair protein
- GeneRad50
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids551 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Publications for E9PUJ2
MRNIP interacts with sex body chromatin to support meiotic progression, spermatogenesis, and male fertility in mice.
- CategoriesFunction, Subcellular Location
- SourceMGI: 109292
MRI is a DNA damage response adaptor during classical non-homologous end joining.
- CategoriesFunction
- SourceMGI: 109292
The MRE11-RAD50-NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair.
- CategoriesFamily & Domains, Function, Interaction
- SourceMGI: 109292
MRE11 Promotes Tumorigenesis by Facilitating Resistance to Oncogene- Induced Replication Stress.
- CategoriesFunction
- SourceMGI: 109292
Generation of a novel, multi-stage, progressive, and transplantable model of plasma cell neoplasms.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 109292
Interdependence of the rad50 hook and globular domain functions.
- CategoriesFunction
- SourceMGI: 109292
Rad50-CARD9 interactions link cytosolic DNA sensing to IL-1beta production.
- CategoriesFunction, Interaction
- SourceMGI: 109292
The Rad50 hook domain regulates DNA damage signaling and tumorigenesis.
- CategoriesFunction
- SourceMGI: 109292
Protective role of RAD50 on chromatin bridges during abnormal cytokinesis.
- CategoriesFunction
- SourceMGI: 109292
Hypersensitive site 6 of the Th2 locus control region is essential for Th2 cytokine expression.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 109292
Aberrant expression of IFN-gamma in Th2 cells from Th2 LCR-deficient mice.
- CategoriesFunction
- SourceMGI: 109292
A conditional knockout resource for the genome-wide study of mouse gene function.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 109292
Regulation of ceramide synthase-mediated crypt epithelium apoptosis by DNA damage repair enzymes.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 109292
Multiple functions of MRN in end-joining pathways during isotype class switching.
- CategoriesFunction
- SourceMGI: 109292
MRN complex function in the repair of chromosomal Rag-mediated DNA double- strand breaks.
- CategoriesFunction
- SourceMGI: 109292
Rad50 is dispensable for the maintenance and viability of postmitotic tissues.
- CategoriesFunction
- SourceMGI: 109292
DNA damage signaling in hematopoietic cells: a role for Mre11 complex repair of topoisomerase lesions.
- CategoriesFunction
- SourceMGI: 109292
Telomere lengthening early in development.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 109292