ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III, Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.[...], Elledge S.J.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCScience 316:1160-1166 (2007)Cited in99+99+Mapped to23
Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L.[...], Ponting C.P.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol. 7:E1000112-E1000112 (2009)Cited in99+99+
A tissue-specific atlas of mouse protein phosphorylation and expression.Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCCell 143:1174-1189 (2010)Cited in99+99+Mapped to6
Modernizing reference genome assemblies.Church D.M., Schneider V.A., Graves T., Auger K., Cunningham F., Bouk N., Chen H.C., Agarwala R., McLaren W.M.[...], Hubbard T.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol 9:e1001091-e1001091 (2011)Cited in99+
No title available.EnsemblCited forIDENTIFICATIONStrainC57BL/6JSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to UniProtKB (JUN-2024)Cited in99+
Computational and biological analysis of 680 kb of DNA sequence from the human 5q31 cytokine gene cluster region.Frazer K.A., Ueda Y., Zhu Y., Gifford V.R., Garofalo M.R., Mohandas N., Martin C.H., Palazzolo M.J., Cheng J.F., Rubin E.M.View abstractCategoriesSequencesSourceMGI: 109292PubMedEurope PMCGenome Res 7:495-512 (1997)Mapped to69
Mouse RAD50 has limited epitopic homology to p53 and is expressed in the adult myocardium.Kim K.K., Daud A.I., Wong S.C., Pajak L., Tsai S.-C., Wang H., Henzel W.J., Field L.J.View abstractCategoriesSequencesSourceMGI: 109292PubMedEurope PMCJ. Biol. Chem. 271:29255-29264 (1996)Cited in1Mapped to7
A Rad50-null mutation in mouse germ cells causes reduced DSB formation, abnormal DSB end resection and complete loss of germ cells.Liu Y., Lin Z., Yan J., Zhang X., Tong M.H.View abstractSourceMGI: 109292PubMedEurope PMCDevelopment 151:dev202312-dev202312 (2024)Mapped to7
The RNA ligase RNA terminal phosphate cyclase B regulates mRNA alternative splicing and is required for mouse oocyte development and maintenance.Zhang H., Jiang J.C., Wu Y.W., Yu Y.S., Wang H.N., Ding N.Z., Fan H.Y.View abstractCategoriesFunctionSourceMGI: 109292PubMedEurope PMCDevelopment 149:dev200497-dev200497 (2022)Mapped to74
MRNIP interacts with sex body chromatin to support meiotic progression, spermatogenesis, and male fertility in mice.Kazi S., Castaneda J.M., Savolainen A., Xu Y., Liu N., Qiao H., Ramirez-Solis R., Nozawa K., Yu Z.[...], Prunskaite-Hyyrylainen R.View abstractCategoriesFunction, Subcellular LocationSourceMGI: 109292PubMedEurope PMCFASEB J 36:e22479-e22479 (2022)Mapped to73
The E3 ubiquitin ligase Cul4b promotes CD4+ T cell expansion by aiding the repair of damaged DNA.Dar A.A., Sawada K., Dybas J.M., Moser E.K., Lewis E.L., Park E., Fazelinia H., Spruce L.A., Ding H.[...], Oliver P.M.View abstractCategoriesInteractionSourceMGI: 109292PubMedEurope PMCPLoS Biol 19:e3001041-e3001041 (2021)Mapped to46
CtIP-BRCA1 complex and MRE11 maintain replication forks in the presence of chain terminating nucleoside analogs.Mohiuddin M., Rahman M.M., Sale J.E., Pearson C.E.View abstractCategoriesFunctionSourceMGI: 109292PubMedEurope PMCNucleic Acids Res 47:2966-2980 (2019)Mapped to43
MRI is a DNA damage response adaptor during classical non-homologous end joining.Hung P.J., Johnson B., Chen B.R., Byrum A.K., Bredemeyer A.L., Yewdell W.T., Johnson T.E., Lee B.J., Deivasigamani S.[...], Sleckman B.P.View abstractCategoriesFunctionSourceMGI: 109292PubMedEurope PMCMol. Cell 71:332-342 (2018)Cited in9Mapped to24
The MRE11-RAD50-NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair.Syed A., Tainer J.A.View abstractCategoriesFamily & Domains, Function, InteractionSourceMGI: 109292PubMedEurope PMCAnnu Rev Biochem 87:263-294 (2018)Mapped to36
MRE11 Promotes Tumorigenesis by Facilitating Resistance to Oncogene- Induced Replication Stress.Spehalski E., Capper K.M., Smith C.J., Morgan M.J., Dinkelmann M., Buis J., Sekiguchi J.M., Ferguson D.O.View abstractCategoriesFunctionSourceMGI: 109292PubMedEurope PMCCancer Res 77:5327-5338 (2017)Mapped to35
RHS6-mediated chromosomal looping and nuclear substructure binding is required for Th2 cytokine gene expression.Hwang S.S., Jang S.W., Lee G.R.View abstractCategoriesFunctionSourceMGI: 109292PubMedEurope PMCBiochim Biophys Acta Gene Regul Mech 1860:383-391 (2017)Mapped to17
Generation of a novel, multi-stage, progressive, and transplantable model of plasma cell neoplasms.Asai T., Hatlen M.A., Lossos C., Ndiaye-Lobry D., Deblasio A., Murata K., Fleisher M., Cortizas E.M., Verdun R.E.[...], Nimer S.D.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 109292PubMedEurope PMCSci Rep 6:22760-22760 (2016)Mapped to11
ATM-Dependent Phosphorylation of All Three Members of the MRN Complex: From Sensor to Adaptor.Lavin M.F., Kozlov S., Gatei M., Kijas A.W.View abstractCategoriesPTM / ProcessingSourceMGI: 109292PubMedEurope PMCBiomolecules 5:2877-2902 (2015)Mapped to17
Interdependence of the rad50 hook and globular domain functions.Hohl M., Kochanczyk T., Tous C., Aguilera A., Krezel A., Petrini J.H.View abstractCategoriesFunctionSourceMGI: 109292PubMedEurope PMCMol Cell 57:479-491 (2015)Mapped to8
Rad50-CARD9 interactions link cytosolic DNA sensing to IL-1beta production.Roth S., Rottach A., Lotz-Havla A.S., Laux V., Muschaweckh A., Gersting S.W., Muntau A.C., Hopfner K.P., Jin L.[...], Ruland J.View abstractCategoriesFunction, InteractionSourceMGI: 109292PubMedEurope PMCNat Immunol 15:538-545 (2014)Mapped to29
Oct-1 regulates IL-17 expression by directing interchromosomal associations in conjunction with CTCF in T cells.Kim L.K., Esplugues E., Zorca C.E., Parisi F., Kluger Y., Kim T.H., Galjart N.J., Flavell R.A.View abstractCategoriesFunctionSourceMGI: 109292PubMedEurope PMCMol Cell 54:56-66 (2014)Mapped to28
The Rad50 hook domain regulates DNA damage signaling and tumorigenesis.Roset R., Inagaki A., Hohl M., Brenet F., Lafrance-Vanasse J., Lange J., Scandura J.M., Tainer J.A., Keeney S., Petrini J.H.View abstractCategoriesFunctionSourceMGI: 109292PubMedEurope PMCGenes Dev 28:451-462 (2014)Mapped to20
Protective role of RAD50 on chromatin bridges during abnormal cytokinesis.Schroder-Heurich B., Wieland B., Lavin M.F., Schindler D., Dork T.View abstractCategoriesFunctionSourceMGI: 109292PubMedEurope PMCFASEB J 28:1331-1341 (2014)Mapped to7
Myelodysplastic syndrome: an inability to appropriately respond to damaged DNA?Zhou T., Hasty P., Walter C.A., Bishop A.J., Scott L.M., Rebel V.I.View abstractSourceMGI: 109292PubMedEurope PMCExp Hematol 41:665-674 (2013)Mapped to39
Hypersensitive site 6 of the Th2 locus control region is essential for Th2 cytokine expression.Williams A., Lee G.R., Spilianakis C.G., Hwang S.S., Eisenbarth S.C., Flavell R.A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 109292PubMedEurope PMCProc Natl Acad Sci U S A 110:6955-6960 (2013)Mapped to7