E9PC15 · E9PC15_HUMAN
- ProteinAcylglycerol kinase, mitochondrial
- GeneAGK
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids394 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
Catalytic activity
- 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H+This reaction proceeds in the forward direction.
- 1-(9Z-octadecenoyl)-sn-glycerol + ATP = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H+This reaction proceeds in the forward direction.
- 1-hexadecanoyl-sn-glycerol + ATP = 1-hexadecanoyl-sn-glycero-3-phosphate + ADP + H+This reaction proceeds in the forward direction.
- 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + ATP = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H+This reaction proceeds in the forward direction.
- ATP + N-(hexanoyl)sphing-4-enine = ADP + H+ + N-hexanoylsphing-4-enine 1-phosphateThis reaction proceeds in the forward direction.
- a 1-acyl-sn-glycerol + ATP = a 1-acyl-sn-glycero-3-phosphate + ADP + H+This reaction proceeds in the forward direction.
- a 2-acylglycerol + ATP = a 2-acyl-sn-glycerol 3-phosphate + ADP + H+This reaction proceeds in the forward direction.
Cofactor
Pathway
Lipid metabolism; glycerolipid metabolism.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | intracellular membrane-bounded organelle | |
Cellular Component | mitochondrial inner membrane | |
Cellular Component | mitochondrial intermembrane space | |
Cellular Component | mitochondrion | |
Molecular Function | kinase activity | |
Biological Process | glycerolipid metabolic process |
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAcylglycerol kinase, mitochondrial
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionE9PC15
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Peripheral membrane protein
Mitochondrion inner membrane ; Peripheral membrane protein
Keywords
- Cellular component
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 449 variants from UniProt as well as other sources including ClinVar and dbSNP.
Genetic variation databases
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 30-171 | DAGKc | ||||
Sequence: AQVKKATVFLNPAACKGKARTLFEKNAAPILHLSGMDVTIVKTDYEGQAKKLLELMENTDVIIVAGGDGTLQEVVTGVLRRTDEATFSKIPIGFIPLGETSSLSHTLFAESGNKVQHITDATLAIVKGETVPLDVLQIKGEK | ||||||
Region | 221-243 | Disordered | ||||
Sequence: QASISYTGPTERPPNEPEETPVQ |
Sequence similarities
Belongs to the AGK family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length394
- Mass (Da)43,797
- Last updated2011-04-05 v1
- Checksum6F1632164E4342F5
Computationally mapped potential isoform sequences
There are 13 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q53H12 | AGK_HUMAN | AGK | 422 | ||
F8WDD1 | F8WDD1_HUMAN | AGK | 46 | ||
E9PG39 | E9PG39_HUMAN | AGK | 244 | ||
A0A3B3IS09 | A0A3B3IS09_HUMAN | AGK | 146 | ||
A0A3B3ISZ0 | A0A3B3ISZ0_HUMAN | AGK | 350 | ||
A0A3B3ISY9 | A0A3B3ISY9_HUMAN | AGK | 330 | ||
A0A3B3ITD0 | A0A3B3ITD0_HUMAN | AGK | 418 | ||
A0A3B3IUC9 | A0A3B3IUC9_HUMAN | AGK | 134 | ||
A0A3B3ITV0 | A0A3B3ITV0_HUMAN | AGK | 138 | ||
A0A3B3ITX7 | A0A3B3ITX7_HUMAN | AGK | 214 | ||
A0A3B3IRM6 | A0A3B3IRM6_HUMAN | AGK | 81 | ||
A0A0G2JLD0 | A0A0G2JLD0_HUMAN | AGK | 51 | ||
A0A0G2JLG5 | A0A0G2JLG5_HUMAN | AGK | 226 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC004918 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AC073878 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AC099547 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |