ENU mutagenesis identifies mice with morbid obesity and severe hyperinsulinemia caused by a novel mutation in leptin.Hong C.J., Tsai P.J., Cheng C.Y., Chou C.K., Jheng H.F., Chuang Y.C., Yang C.N., Lin Y.T., Hsu C.W.[...], Tsai Y.S.View abstractCited forNUCLEOTIDE SEQUENCEStrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS One 5:e15333-e15333 (2010)Cited in1Mapped to4
ENU Mutagenesis Identifies Mice with Morbid Obesity and Severe Hyperinsulinemia Caused by a Novel Mutation in Leptin.Hong C.-J.Cited forNUCLEOTIDE SEQUENCEStrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to EMBL/GenBank/DDBJ databases (AUG-2010)Cited in1
Plasma insulin rise precedes rise in ob mRNA expression and plasma leptin in gold thioglucose-obese mice.Bryson J.M., Phuyal J.L., Proctor D.R., Blair S.C., Caterson I.D., Cooney G.J.View abstractCategoriesExpressionSourceMGI: 104663PubMedEurope PMCAm J Physiol 276:E358-64 (1999)Mapped to5
Phenotypic abnormalities in macrophages from leptin-deficient, obese mice.Lee F.Y., Li Y., Yang E.K., Yang S.Q., Lin H.Z., Trush M.A., Dannenberg A.J., Diehl A.M.View abstractCategoriesFunctionSourceMGI: 104663PubMedEurope PMCAm J Physiol 276:C386-94 (1999)Mapped to24
Neuroendocrine peptides of the gastrointestinal tract of an animal model of human type 2 diabetes mellitus.El-Salhy M.View abstractCategoriesSequencesSourceMGI: 104663PubMedEurope PMCActa Diabetol 35:194-198 (1998)Mapped to11
Increased high density lipoprotein (HDL), defective hepatic catabolism of ApoA-I and ApoA-II, and decreased ApoA-I mRNA in ob/ob mice. Possible role of leptin in stimulation of HDL turnover.Silver D.L., Jiang X.C., Tall A.R.View abstractCategoriesFunctionSourceMGI: 104663PubMedEurope PMCJ Biol Chem 274:4140-4146 (1999)Mapped to11
Hypothalamic agouti-related protein messenger ribonucleic acid is inhibited by leptin and stimulated by fasting.Mizuno T.M., Mobbs C.V.View abstractCategoriesSequences, ExpressionSourceMGI: 104663PubMedEurope PMCEndocrinology 140:814-817 (1999)Mapped to10
Effect of the genetic background on the reproduction of leptin-deficient obese mice.Ewart-Toland A., Mounzih K., Qiu J., Chehab F.F.View abstractCategoriesPhenotypes & VariantsSourceMGI: 104663PubMedEurope PMCEndocrinology 140:732-738 (1999)Mapped to5
Review: Central non-glucocorticoid inhibitors of the hypothalamo- pituitary-adrenal axis.Jessop D.S.CategoriesFunction, SequencesSourceMGI: 104663PubMedEurope PMCJ Endocrinol 160:169-180 (1999)Mapped to47
Genetic analysis of non-insulin-dependent diabetes mellitus in KK and KK- Ay mice.Suto J., Matsuura S., Imamura K., Yamanaka H., Sekikawa K.View abstractCategoriesSequences, Phenotypes & VariantsSourceMGI: 104663PubMedEurope PMCEur J Endocrinol 139:654-661 (1998)Mapped to11
Leptin inhibits insulin gene transcription and reverses hyperinsulinemia in leptin-deficient ob/ob mice.Seufert J., Kieffer T.J., Habener J.F.View abstractCategoriesSequencesSourceMGI: 104663PubMedEurope PMCProc Natl Acad Sci U S A 96:674-679 (1999)Mapped to13
Regulation of putative fatty acid transporters and Acyl-CoA synthetase in liver and adipose tissue in ob/ob mice.Memon R.A., Fuller J., Moser A.H., Smith P.J., Grunfeld C., Feingold K.R.View abstractCategoriesExpressionSourceMGI: 104663PubMedEurope PMCDiabetes 48:121-127 (1999)Mapped to21
Leptin deficiency enhances sensitivity to endotoxin-induced lethality.Faggioni R., Fantuzzi G., Gabay C., Moser A., Dinarello C.A., Feingold K.R., Grunfeld C.View abstractCategoriesFunctionSourceMGI: 104663PubMedEurope PMCAm J Physiol 276:R136-42 (1999)Mapped to11
Induction of uncoupling protein expression in brown and white adipose tissue by leptin.Commins S.P., Watson P.M., Padgett M.A., Dudley A., Argyropoulos G., Gettys T.W.View abstractCategoriesExpressionSourceMGI: 104663PubMedEurope PMCEndocrinology 140:292-300 (1999)Mapped to6
Parabiosis between db/db and ob/ob or db/+ mice.Harris R.B.View abstractCategoriesFunctionSourceMGI: 104663PubMedEurope PMCEndocrinology 140:138-145 (1999)Mapped to11
Test of candidate gene--quantitative trait locus association applied to fatness in mice.Keightley P.D., Morris K.H., Ishikawa A., Falconer V.M., Oliver F.View abstractCategoriesSequences, Phenotypes & VariantsSourceMGI: 104663PubMedEurope PMCHeredity (Edinb) 81:630-637 (1998)Mapped to24
Leptin is an endogenous protective protein against the toxicity exerted by tumor necrosis factor.Takahashi N., Waelput W., Guisez Y.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 104663PubMedEurope PMCJ Exp Med 189:207-212 (1999)Mapped to17
Neuropeptide Y and corticotropin-releasing hormone concentrations within specific hypothalamic regions of lean but not ob/ob mice respond to food- deprivation and refeeding.Jang M., Romsos D.R.View abstractCategoriesExpressionSourceMGI: 104663PubMedEurope PMCJ Nutr 128:2520-2525 (1998)Mapped to7
Functional analysis of tumor necrosis factor (TNF) receptors in TNF-alpha- mediated insulin resistance in genetic obesity.Uysal K.T., Wiesbrock S.M., Hotamisligil G.S.View abstractCategoriesFunctionSourceMGI: 104663PubMedEurope PMCEndocrinology 139:4832-4838 (1998)Mapped to19
Endothelin ETA receptor blockade restores NO-mediated endothelial function and inhibits atherosclerosis in apolipoprotein E-deficient mice.Barton M., Haudenschild C.C., d'Uscio L.V., Shaw S., Munter K., Luscher T.F.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 104663PubMedEurope PMCProc Natl Acad Sci U S A 95:14367-14372 (1998)Mapped to28
Insulin depletion leads to adipose-specific cell death in obese but not lean mice.Loftus T.M., Kuhajda F.P., Lane M.D.View abstractCategoriesFunctionSourceMGI: 104663PubMedEurope PMCProc Natl Acad Sci U S A 95:14168-14172 (1998)Mapped to5
Agouti/melanocortin interactions with leptin pathways in obesity.Zemel M.B.View abstractCategoriesSequencesSourceMGI: 104663PubMedEurope PMCNutr Rev 56:271-274 (1998)Mapped to27
Abnormal regulation of the leptin gene in the pathogenesis of obesity.Ioffe E., Moon B., Connolly E., Friedman J.M.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 104663PubMedEurope PMCProc Natl Acad Sci U S A 95:11852-11857 (1998)Mapped to5
Leptin action in intestinal cells.Morton N.M., Emilsson V., Liu Y.L., Cawthorne M.A.View abstractCategoriesExpressionSourceMGI: 104663PubMedEurope PMCJ Biol Chem 273:26194-26201 (1998)Mapped to5
Leptin modulates the T-cell immune response and reverses starvation- induced immunosuppression.Lord G.M., Matarese G., Howard J.K., Baker R.J., Bloom S.R., Lechler R.I.View abstractCategoriesFunctionSourceMGI: 104663PubMedEurope PMCNature 394:897-901 (1998)Cited in2Mapped to9