E9HK77 · E9HK77_DAPPU
- Proteindolichyl-phosphate-mannose--protein mannosyltransferase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids705 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Transfers mannosyl residues to the hydroxyl group of serine or threonine residues.
Catalytic activity
- a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H+
a di-trans,poly-cis-dolichyl β-D-mannosyl phosphate RHEA-COMP:19501 + RHEA-COMP:9863 = RHEA-COMP:13546 + a di-trans,poly-cis-dolichyl phosphate RHEA-COMP:19498 + CHEBI:15378
Pathway
Protein modification; protein glycosylation.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum membrane | |
Molecular Function | dolichyl-phosphate-mannose-protein mannosyltransferase activity | |
Molecular Function | mannosyltransferase activity | |
Biological Process | protein O-linked mannosylation |
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namedolichyl-phosphate-mannose--protein mannosyltransferase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Crustacea > Branchiopoda > Diplostraca > Cladocera > Anomopoda > Daphniidae > Daphnia
Accessions
- Primary accessionE9HK77
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 89-109 | Helical | ||||
Sequence: WHHWINVMLHCAVTSAVTLIA | ||||||
Transmembrane | 144-164 | Helical | ||||
Sequence: GLVGRADMVCTLFFLAGLFTY | ||||||
Transmembrane | 185-204 | Helical | ||||
Sequence: YGIMLTPVCLLYDLVVFSRS | ||||||
Transmembrane | 210-230 | Helical | ||||
Sequence: IFNWVVLTAWSIALMTFRFWL | ||||||
Transmembrane | 251-273 | Helical | ||||
Sequence: WTTRSLTFLYLPVFHFGLLLWPR | ||||||
Transmembrane | 293-310 | Helical | ||||
Sequence: IRNLATLIFYTVLAVAIR | ||||||
Transmembrane | 322-347 | Helical | ||||
Sequence: IVLALAVITTTIPFLPATNLFAYVGF | ||||||
Transmembrane | 353-373 | Helical | ||||
Sequence: ILYLPSVGFCLLVGLGVQMLI | ||||||
Transmembrane | 380-398 | Helical | ||||
Sequence: QMIFGSILILLLASGWRTI |
Keywords
- Cellular component
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, repeat.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 233-305 | DUF1736 | ||||
Sequence: FHTPQFARADNPTAASPSWTTRSLTFLYLPVFHFGLLLWPRWLSFDWSMDAIQPVTSLKDIRNLATLIFYTVL | ||||||
Repeat | 420-453 | TPR | ||||
Sequence: PKAHGNLGVVFQQSGRLTEAEWNFKRALSYRPNM | ||||||
Repeat | 454-487 | TPR | ||||
Sequence: ADVHHNLGNLFQQQSRYEESLQAYNKAIHFRPQL | ||||||
Repeat | 572-605 | TPR | ||||
Sequence: PLVYYQLGEFLSARSRHNEAAEVLIQAAEMDPNN | ||||||
Repeat | 640-673 | TPR | ||||
Sequence: ISHRLNLGAVLHVQGKLDEAEQVYLKALRLSPNH |
Sequence similarities
Belongs to the TMTC family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length705
- Mass (Da)80,191
- Last updated2011-04-05 v1
- ChecksumAF5EE244FC8718CF
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
GL732667 EMBL· GenBank· DDBJ | EFX67835.1 EMBL· GenBank· DDBJ | Genomic DNA |