E9HHQ5 · E9HHQ5_DAPPU
- Proteinreceptor protein-tyrosine kinase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids419 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
Catalytic activity
- L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H+
Features
Showing features for binding site, active site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 21-28 | ATP (UniProtKB | ChEBI) | |||
Binding site | 49 | ATP (UniProtKB | ChEBI) | |||
Active site | 198 | Proton acceptor | |||
Binding site | 202 | ATP (UniProtKB | ChEBI) | |||
Binding site | 203 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 216 | Mg2+ (UniProtKB | ChEBI) | |||
Site | 364 | Important for interaction with phosphotyrosine-binding proteins | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Cellular Component | receptor complex | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | transmembrane receptor protein tyrosine kinase activity | |
Biological Process | cell surface receptor protein tyrosine kinase signaling pathway | |
Biological Process | protein phosphorylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namereceptor protein-tyrosine kinase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Crustacea > Branchiopoda > Diplostraca > Cladocera > Anomopoda > Daphniidae > Daphnia
Accessions
- Primary accessionE9HHQ5
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Single-pass membrane protein
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, compositional bias, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 14-365 | Protein kinase | |||
Compositional bias | 393-411 | Basic and acidic residues | |||
Region | 393-419 | Disordered | |||
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length419
- Mass (Da)47,477
- Last updated2011-04-05 v1
- ChecksumD4C5488D1A1B6772
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 393-411 | Basic and acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
GL732649 EMBL· GenBank· DDBJ | EFX68746.1 EMBL· GenBank· DDBJ | Genomic DNA |