E9G227 · E9G227_DAPPU

Function

Catalytic activity

Features

Showing features for binding site, active site.

115752004006008001,0001,2001,400
TypeIDPosition(s)Description
Binding site546-554ATP (UniProtKB | ChEBI)
Binding site569ATP (UniProtKB | ChEBI)
Active site752Proton acceptor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentcytosol
Cellular Componentnucleus
Molecular FunctionATP binding
Molecular Functioneukaryotic translation initiation factor 2alpha kinase activity
Biological ProcessDNA damage checkpoint signaling
Biological Processnegative regulation of cytoplasmic translational initiation in response to stress

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    non-specific serine/threonine protein kinase
  • EC number

Gene names

    • ORF names
      DAPPUDRAFT_313217

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Crustacea > Branchiopoda > Diplostraca > Cladocera > Anomopoda > Daphniidae > Daphnia

Accessions

  • Primary accession
    E9G227

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain15-128RWD
Domain257-496Protein kinase
Domain540-915Protein kinase
Region611-697Disordered
Compositional bias633-671Polar residues
Compositional bias672-686Acidic residues
Region1419-1438Disordered

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,575
  • Mass (Da)
    177,933
  • Last updated
    2011-04-05 v1
  • Checksum
    56F2B6FB408CDDAA
MNVEEEESLEVRQRNEIQALQAIFTSDFVAVNLSSNSEKWSPPEFILLLKPQKGLSQDEVHATVQLRVKFPCDYPQSYPSIKLENGEGISSKDIEKLQLELEQLCKEGVGEEVTFNLAHHAQGFLAERNQKPRFQSFHEEMLAAQRNNMEKSVLEEKSRQVREDEQQLIAFCEEIQKKQPALLSELRRITNLDPNQLPFLEINLGSSQTSNTNEDQSNLDHTIEAQKLCTHPKVQKISFSNKDGGRIYYCGPCLGVCRPNRYICAGVEPNLKEAATITTFQISCGNLESRRKQISLVEQEFRLLQRNVHHSALIPLLAFKWEMSEDEECFYLYVAEQLVPGLSLNFFINRGFSVSVDILRHITGSILQALQVLHRANVVHKNLRHSSIFLDSFGEVKVGDYSLESRINEIFSIQDDRPSLSMYPSAPGRGGKRGDIHRLGILLWTLYQGNIVHRWDCLKLPSSMPLLLRDLIGKCIGSDIEKDRMSIDEVLSHAFLKTPIFREHQEQEESRDDDKFRSDVPQVAFRTEMPHIPSRLLSEFETLQFLGSGGFGDVLKVRNKLDGNIYAIKRILLDAKSRQLNKKITREVKLLSRLNHENIVRYYNSWLETVQTDSPSRSGHSESRDDPKVNGMKQNNVAESDSSDLSHSRGPWFIKPQESSSSGGIEFDSDGIESSSSEEEESSKEEDTVDAPNSSSRSLQSMYIQMEYCEKSTLRTAIDSELFRDKPRIWRLFREIVEGLAYIHLQGIIHRDLKPVNIFLDSEDRVKIGDFGLATSSPLTTLATAATVDAIDGASNRIALSNDKSSEIASNSGQLTGQIGTVLYVAPELKATGKTNYNEKVDIYSLGIIFFEMCHPPLLTGMERIKVLSSLRLPEIVLPVSDNLTGKEVQLINWLLNHNPSARPSSTELLQSPILPPPQLEEAELQEMIRHTLSNTQSKAYKHLVASCFQQKMTISEDLVYNMDMTSSAGLQQSAWIFQAVQEVFVKHCQRRGAIYFKTPTLSPKKGQPNQGFSQVLLMNHAGSIVTLPTDLQTPFARFISRSNLTWLKRYCIDYVYSERKLVGLHPKSFPELAFDIVTPSPSSVLADAEVLVTISDVFSDQRLKIERKITLELGHHLLLKAVLIHCGIPEDKRSELCHILKTRSKSEGQIQNKTAKLAISRQSIDMLLNLLELEGSVAKVTAALTNLISRKGEAASLAKQALHELDAVATHAECMGLRNTYSIRIDTALQNYTTHWGMVFRFVCRSNLRKTKIDDVLATGGRYDALVRSFQNALVNRKKVDGEPMSQPTVVGGLIHLDRVAAILKETEVVEERVLVYVAICTVGYRPQTKEQASLVKDLWNNGVRATVLDHCQSLDEAQIWCREKNVPHIVILKDSEVGSARLKTWEKDRYTERKMMLGELIDVLKCSAESASDTTESFVSHTRQDSMNRSNSLSETCGNQTATSLQGIAGNPIVNFHIVIEEKLPVHARKRYEKQILKHIQTTLQNFHSRVQVDIVAIEATAVVVQSLLIALYVDPSDAKAVEQAIGVVVDKHRRQRKYLQRIYEQLLQLKFEKHVTVLMIYGLHDNSSRICM

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias633-671Polar residues
Compositional bias672-686Acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GL732530
EMBL· GenBank· DDBJ
EFX86379.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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