E9G227 · E9G227_DAPPU
- Proteinnon-specific serine/threonine protein kinase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1575 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | cytosol | |
Cellular Component | nucleus | |
Molecular Function | ATP binding | |
Molecular Function | eukaryotic translation initiation factor 2alpha kinase activity | |
Biological Process | DNA damage checkpoint signaling | |
Biological Process | negative regulation of cytoplasmic translational initiation in response to stress |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namenon-specific serine/threonine protein kinase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Crustacea > Branchiopoda > Diplostraca > Cladocera > Anomopoda > Daphniidae > Daphnia
Accessions
- Primary accessionE9G227
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 15-128 | RWD | ||||
Sequence: NEIQALQAIFTSDFVAVNLSSNSEKWSPPEFILLLKPQKGLSQDEVHATVQLRVKFPCDYPQSYPSIKLENGEGISSKDIEKLQLELEQLCKEGVGEEVTFNLAHHAQGFLAER | ||||||
Domain | 257-496 | Protein kinase | ||||
Sequence: CRPNRYICAGVEPNLKEAATITTFQISCGNLESRRKQISLVEQEFRLLQRNVHHSALIPLLAFKWEMSEDEECFYLYVAEQLVPGLSLNFFINRGFSVSVDILRHITGSILQALQVLHRANVVHKNLRHSSIFLDSFGEVKVGDYSLESRINEIFSIQDDRPSLSMYPSAPGRGGKRGDIHRLGILLWTLYQGNIVHRWDCLKLPSSMPLLLRDLIGKCIGSDIEKDRMSIDEVLSHAFL | ||||||
Domain | 540-915 | Protein kinase | ||||
Sequence: FETLQFLGSGGFGDVLKVRNKLDGNIYAIKRILLDAKSRQLNKKITREVKLLSRLNHENIVRYYNSWLETVQTDSPSRSGHSESRDDPKVNGMKQNNVAESDSSDLSHSRGPWFIKPQESSSSGGIEFDSDGIESSSSEEEESSKEEDTVDAPNSSSRSLQSMYIQMEYCEKSTLRTAIDSELFRDKPRIWRLFREIVEGLAYIHLQGIIHRDLKPVNIFLDSEDRVKIGDFGLATSSPLTTLATAATVDAIDGASNRIALSNDKSSEIASNSGQLTGQIGTVLYVAPELKATGKTNYNEKVDIYSLGIIFFEMCHPPLLTGMERIKVLSSLRLPEIVLPVSDNLTGKEVQLINWLLNHNPSARPSSTELLQSPIL | ||||||
Region | 611-697 | Disordered | ||||
Sequence: QTDSPSRSGHSESRDDPKVNGMKQNNVAESDSSDLSHSRGPWFIKPQESSSSGGIEFDSDGIESSSSEEEESSKEEDTVDAPNSSSR | ||||||
Compositional bias | 633-671 | Polar residues | ||||
Sequence: KQNNVAESDSSDLSHSRGPWFIKPQESSSSGGIEFDSDG | ||||||
Compositional bias | 672-686 | Acidic residues | ||||
Sequence: IESSSSEEEESSKEE | ||||||
Region | 1419-1438 | Disordered | ||||
Sequence: SFVSHTRQDSMNRSNSLSET |
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,575
- Mass (Da)177,933
- Last updated2011-04-05 v1
- Checksum56F2B6FB408CDDAA
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 633-671 | Polar residues | ||||
Sequence: KQNNVAESDSSDLSHSRGPWFIKPQESSSSGGIEFDSDG | ||||||
Compositional bias | 672-686 | Acidic residues | ||||
Sequence: IESSSSEEEESSKEE |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
GL732530 EMBL· GenBank· DDBJ | EFX86379.1 EMBL· GenBank· DDBJ | Genomic DNA |