E9FB59 · E9FB59_METRA
- ProteinGlutathione hydrolase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids567 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
function
Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
Catalytic activity
- an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate
Pathway
Sulfur metabolism; glutathione metabolism.
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | glutathione hydrolase activity | |
Molecular Function | leukotriene C4 gamma-glutamyl transferase activity | |
Biological Process | glutathione catabolic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlutathione hydrolase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Clavicipitaceae > Metarhizium
Accessions
- Primary accessionE9FB59
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-24 | |||||
Sequence: MLFNITKILNYLLLIASTPTIVYG | ||||||
Chain | PRO_5003239822 | 25-567 | Glutathione hydrolase | |||
Sequence: EEQNYGTNHGAVASESKICSEIGTQLLQKCHGGRCGNAVDALVGTVFCVGTVAMYHSGIGGGGFALVRLPNGTYKSVDFREVAPDAAHENMYQGNIDGSKIGGLASAVPGEVKGLKYIHENYGNLRWADVMAPAIKLARYGFPVSKDLVTYMDLTTPNSFFTDEKEWAIDFAPQGHRVRYGEIMTRERYANTLEDIANRGPKAFYTGHIAEATIRALKSRNGCMELEDLERYNFTLPDPVKIQYRDYSLTSINAPSSGIVALSALNILGGFLDFEEPRQSNSSTHRMIEAIKWGYGQRKGLGDPSFVALGQYTKNMISKETGDWIRSKISDNQTFDDDYYDVDGTELLKTPGTSHIVTADASGMSVSMTTTINLYFGSHVMVPETGVIMNNEMNDFDIPSERNRFGLDSNKANFIQGRKRPLSAISPIIAETSDNKLLFSIGCAGGIRITTANIQNAIHLLDGKMTTLEALSEPRLHAQLGQARNVTIEGGYDNGVIGFLESLGHGINRGPAQTSAQGLRRLPDGSFEAAAEPRQCNSGASVV |
Structure
Sequence
- Sequence statusComplete
- Length567
- Mass (Da)61,736
- Last updated2015-03-04 v2
- ChecksumBF807A7018557214
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
ADNJ02000004 EMBL· GenBank· DDBJ | EFY95059.2 EMBL· GenBank· DDBJ | Genomic DNA |