E9F3B8 · E9F3B8_METRA

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2.
Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2.

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Function(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity
Molecular FunctionN6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity
Biological Process'de novo' AMP biosynthetic process
Biological Process'de novo' IMP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenylosuccinate lyase
  • EC number
  • Short names
    ASL
  • Alternative names
    • Adenylosuccinase

Gene names

    • ORF names
      MAA_06767

Organism names

Accessions

  • Primary accession
    E9F3B8

Proteomes

Subcellular Location

Interaction

Subunit

Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain383-467Adenylosuccinate lyase C-terminal

Sequence similarities

Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    494
  • Mass (Da)
    55,321
  • Last updated
    2011-04-05 v1
  • Checksum
    CE03152C2120CDB3
MATAGKNAGPSPYDTYQTSLTTRYCSPEMARLFGQRSRHSQWRRLWLLLAESERELGIQTITTEALEQMKQHLEVTDQDFEVARAEEKIRRHDVMAHVHAFGAVAPAAAGIIHYGATSCFVTDNAELILMRDAMDLLLPRLAKVVSNLCQLAREWKATPTLAYTHLQPAQLITVGKRAAQWAQDLVFDLESIEHVRNGLLLRGAQGTTGTQASFLEIFGGDGSKCDQLNALLCKKTDFPACYDVSTQTYTRKVDLLVANAICGLGATAQKIAGDIRHLASWQEAEEPFEDKQVGSSAMPFKRNPMRSERVSSLARELLSKQATTANTLAAQWMERSLDDSAVRRMDLPEMFLLADAIIGSLDNITDGMVIYPQVIASRVHQQLPFMCAENIIMKLTAKGISRQEAHEQIRVLSHQAARVVKLEGKPNDLIDRIKATEFFQPIWADLDDMLRPELYIGRSIEIVERYCGLEGVAEKKIQRYRAVFEKSQTTELNV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ADNJ02000011
EMBL· GenBank· DDBJ
EFY97984.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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