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E9F337 · E9F337_METRA

Function

function

ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G2/M. May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres. Has a specific role in chromosome segregation during meiosis II.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

GO annotations

AspectTerm
Cellular Componentnucleus
Molecular FunctionATP binding
Molecular FunctionDNA binding
Molecular FunctionDNA helicase activity
Molecular Functionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
Molecular Functioniron-sulfur cluster binding
Molecular Functionisomerase activity
Molecular Functionmetal ion binding
Biological Processestablishment of sister chromatid cohesion
Biological Processnucleobase-containing compound metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent DNA helicase CHL1
  • EC number
  • Alternative names
    • ATP-dependent DNA helicase chl1
    • Chromosome loss protein 1
    • DNA 5'-3' helicase CHL1

Gene names

    • ORF names
      MAA_06686

Organism names

Accessions

  • Primary accession
    E9F337

Proteomes

Subcellular Location

Keywords

  • Cellular component

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain17-432Helicase ATP-binding

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    895
  • Mass (Da)
    99,086
  • Last updated
    2015-03-04 v2
  • MD5 Checksum
    B446EEC350FD73E920BCB72E4B9674FC
MASAATTSVDDATRHLEKLDFHHPYTPYAVQEQFMRTVYDILDKGEGQVGILESPTGTGKSLSLICASLTWLRNFKSNKVEVSMQNAGDAYKDEPAWLVDQLLRRKREELVQRWEDREKRLEAIRLKEKALEDRGRKRRRLEEAITPGDGNDMDADEAEWLLNEWGDRDTGVQTALSGLSKESREVLERIGLGGPRKKEEDNDILEEEVKIYYTSRTHSQLSQFITELRRPKFPSSLPTSLAEKKSSVEETVKLLPLSSRQRLCINPSVARLGSVQAINDRCAELQQSKSTKKCPYVPKEELLSQTHQFRDSALATVPDIEDLHQLGKSLAVCPYYASRSALPGAEIITLPYPLLLQRSAREALGIKLEGNVVIIDEAHNVMDAVANVHAAEIKLSDLHKGRGMLGIYVKRFGKKLKGVNRVNVGRVGRVIDGLTEWMNGAKGFKLIPRQQQHGIVDANDLTRPKGIDQINMFELIQYIQESKLAYKIESYAAHVENENDSGKPGTKSSTPVLHTLVSFLVALTNPSSEGRIFYQKTSGPAQDVQLSYLLLSPTHAFSSIVSSARAVILAGGTMSPFDDYKNHLFPALADPKVTTLSCGHVIPRENLCVWTLTGTRPGGSSFEFSYQRRGDSEMVKELGLAILNICSVVPDGVVVFFPSYGYLEEVVAAWSRRAPGDKNPQTTIWDRLQTRKMVFRETKGCSSDEVLQEYSQAILGNGGSTTGLVKGKGGALLLSVVGGKMSEGINFSDRLGRCVMVVGLPYPNIASPEWKAKMDYIESTTLANLQDSRRDAGPKLTKDEAAARAKQAARDFYENACMRAVNQSIGRAIRHKGDYAAIVLADRRYATERIQGKLPGWIRSGMDARGSGGDGKASMNMLGGLMGSLGGFFRDKQRE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ADNJ02000011
EMBL· GenBank· DDBJ
EFY97903.2
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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