E9EU60 · E9EU60_METRA
- ProteinPyruvate dehydrogenase E1 component subunit alpha
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids409 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
function
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
Catalytic activity
- H+ + N6-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + pyruvate = CO2 + N6-[(R)-S8-acetyldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase]
Cofactor
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | intracellular membrane-bounded organelle | |
Molecular Function | pyruvate dehydrogenase (acetyl-transferring) activity | |
Biological Process | acetyl-CoA biosynthetic process from pyruvate |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePyruvate dehydrogenase E1 component subunit alpha
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Clavicipitaceae > Metarhizium
Accessions
- Primary accessionE9EU60
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 84-379 | Dehydrogenase E1 component | ||||
Sequence: YDMVTIRQMEMAADRLYKEKKIRGFCHLSTGQEAVAVGIEHAITKLDDVITAYRCHGFALMRGGTVRSIIGELLGRREGIAYGKGGSMHMFSKGFYGGNGIVGAQVPVGAGLAFAHKYNDSKTASIILYGDGASNQGQVFEAFNMAKLWNLPALFGCENNKYGMGTSAARSSALTDYYKRGQYIPGLKVNGMDVLAVKAAVTYGKEWTAADKGPMVLEYVTYRYGGHSMSDPGTTYRTREEIQRMRSTNDPIAGLKQKILDWEVTTEDELKKIDKEARSHVNEEVAIAEAMAVPEP |
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length409
- Mass (Da)45,409
- Last updated2011-04-05 v1
- ChecksumAC1B724036B80240
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
ADNJ02000003 EMBL· GenBank· DDBJ | EFZ00963.1 EMBL· GenBank· DDBJ | Genomic DNA |