E9ERN9 · E9ERN9_METRA

Function

function

Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Sulfur metabolism; glutathione metabolism.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site107L-glutamate (UniProtKB | ChEBI)
Active site382Nucleophile
Binding site400-402L-glutamate (UniProtKB | ChEBI)
Binding site424L-glutamate (UniProtKB | ChEBI)
Binding site452-453L-glutamate (UniProtKB | ChEBI)
Binding site475L-glutamate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionglutathione hydrolase activity
Molecular Functionleukotriene C4 gamma-glutamyl transferase activity
Biological Processglutathione catabolic process

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Glutathione hydrolase
  • EC number
  • Alternative names
    • Gamma-glutamyltransferase
    • Gamma-glutamyltranspeptidase

Gene names

    • ORF names
      MAA_02635

Organism names

Accessions

  • Primary accession
    E9ERN9

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-25
ChainPRO_500323877826-572Glutathione hydrolase

Family & Domains

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    572
  • Mass (Da)
    61,740
  • Last updated
    2015-03-04 v2
  • Checksum
    2D1A71B28287F2BF
MVETLMPHLARLLLASLANYGFTHASALPEVVFRPTTDGSLGAVASESAECSAIGRDLLARGGNAADALVGTTFCVGVIGMYHSGIGGGGFAIVRDSAGNYEAVDFREAAPAAGHEDMYQGNVPGSIYGGLAVGVPSEVLGLEYIHSKYGSLPWKTVMQGAIHVARHGFRVSNDLVGYIERAVKEKPNFLVEDPNWAQDFAPNGSLLQVGEIMTRKRYANTLEKIANQGSKVFYTGELAETLVNYIQQTNGTLTLSDFKNYKVISRPVKNVTYRGLHLYTIGTPASGSITLNILKIMEQFDEADSKDTNLTSHRFVEAMRFGYGARAELGDPAFVEGLDEYEAHLLDDVHAKQIRERISDKQTLPVREYNPKGVALPESHGTSHIVTADRSGMATSLTTTVNLLFGAQIMDPSSGIILNNEMNDFSIPGVPNEFGFQPSVANFIRPGKRPLSSVTPVIAAFPDGKLFATVGAAGGSRIISSTTSALWHTIEQEMTMKEALREPRLHDQVMPNTLLLEYGFDAETAAGLGERKHNITWVGPGLSAVQGIRRLRDGSFEAASEPRQKNSGGFTI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ADNJ02000004
EMBL· GenBank· DDBJ
EFZ01406.2
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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